Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.05
  2. 1968223Class h: Coiled coil proteins [57942] (7 folds)
  3. 1968224Fold h.1: Parallel coiled-coil [57943] (35 superfamilies)
    this is not a true fold; includes oligomers of shorter identical helices
  4. 1969135Superfamily h.1.15: SNARE fusion complex [58038] (2 families) (S)
    tetrameric parallel coiled coil
  5. 1969136Family h.1.15.1: SNARE fusion complex [58039] (12 proteins)
  6. 1969166Protein Synaptosomal-associated protein SNAP-25 [88915] (3 species)
    provides up to two different helical regions to synaptic fusion complexes
  7. 1969167Species Human (Homo sapiens) [TaxId:9606] [88917] (4 PDB entries)
    Uniprot P60880 146-204 # identical sequence to rat species

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1kil:
    1. 1969173Domain d1kilc_: 1kil C: [72520]
      Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
      complex with syntaxin, synaptobrevin and complexin fragments
      complexed with mg
    2. 1969174Domain d1kild_: 1kil D: [72521]
      Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
      complex with syntaxin, synaptobrevin and complexin fragments
      complexed with mg
  2. Domain(s) for 1xtg:
    • 1969172Domain d1xtgb_: 1xtg B: [116021]
      Other proteins in same PDB: d1xtga_
      complexed the catalytic domain of the botulinum neurotoxin
      complexed with cl, zn
  3. Domain(s) for 2n1t:
  4. Domain(s) for 3rk2:
    1. 1969168Domain d3rk2c_: 3rk2 C: [249133]
      Other proteins in same PDB: d3rk2b_, d3rk2f_
      automated match to d1n7sc_
      complexed with ca
    2. 1969169Domain d3rk2d_: 3rk2 D: [249134]
      Other proteins in same PDB: d3rk2b_, d3rk2f_
      automated match to d1kild_
      complexed with ca
    3. 1969170Domain d3rk2g_: 3rk2 G: [249136]
      Other proteins in same PDB: d3rk2b_, d3rk2f_
      automated match to d1n7sc_
      complexed with ca
    4. 1969171Domain d3rk2h_: 3rk2 H: [249137]
      Other proteins in same PDB: d3rk2b_, d3rk2f_
      automated match to d1kild_
      complexed with ca

More info for Species Human (Homo sapiens) [TaxId:9606] from h.1.15.1 Synaptosomal-associated protein SNAP-25

Timeline for Species Human (Homo sapiens) [TaxId:9606] from h.1.15.1 Synaptosomal-associated protein SNAP-25: