Lineage for Protein: Synaptosomal-associated protein SNAP-25

  1. Root: SCOPe 2.05
  2. 1968223Class h: Coiled coil proteins [57942] (7 folds)
  3. 1968224Fold h.1: Parallel coiled-coil [57943] (35 superfamilies)
    this is not a true fold; includes oligomers of shorter identical helices
  4. 1969135Superfamily h.1.15: SNARE fusion complex [58038] (2 families) (S)
    tetrameric parallel coiled coil
  5. 1969136Family h.1.15.1: SNARE fusion complex [58039] (12 proteins)
  6. 1969166Protein Synaptosomal-associated protein SNAP-25 [88915] (3 species)
    provides up to two different helical regions to synaptic fusion complexes

Species:

  1. 1969167Human (Homo sapiens) [TaxId:9606] [88917] (4 PDB entries)
    Uniprot P60880 146-204 # identical sequence to rat species
    1. Domains for 1kil:
      1. 1969173Domain d1kilc_: 1kil C: [72520]
        Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
        complex with syntaxin, synaptobrevin and complexin fragments
        complexed with mg
      2. 1969174Domain d1kild_: 1kil D: [72521]
        Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
        complex with syntaxin, synaptobrevin and complexin fragments
        complexed with mg
    2. Domain for 1xtg:
      • 1969172Domain d1xtgb_: 1xtg B: [116021]
        Other proteins in same PDB: d1xtga_
        complexed the catalytic domain of the botulinum neurotoxin
        complexed with cl, zn
    3. Domain for 2n1t:
    4. Domains for 3rk2:
      1. 1969168Domain d3rk2c_: 3rk2 C: [249133]
        Other proteins in same PDB: d3rk2b_, d3rk2f_
        automated match to d1n7sc_
        complexed with ca
      2. 1969169Domain d3rk2d_: 3rk2 D: [249134]
        Other proteins in same PDB: d3rk2b_, d3rk2f_
        automated match to d1kild_
        complexed with ca
      3. 1969170Domain d3rk2g_: 3rk2 G: [249136]
        Other proteins in same PDB: d3rk2b_, d3rk2f_
        automated match to d1n7sc_
        complexed with ca
      4. 1969171Domain d3rk2h_: 3rk2 H: [249137]
        Other proteins in same PDB: d3rk2b_, d3rk2f_
        automated match to d1kild_
        complexed with ca
  2. 1969176Longfin inshore squid (Loligo pealei) [TaxId:6621] [88918] (1 PDB entry)
  3. 1969179Norway rat (Rattus norvegicus) [TaxId:10116] [88916] (4 PDB entries)
    Uniprot P13795 7-83; 142-204 # identical sequences to human species
    1. Domains for 1jth:
      1. 1969184Domain d1jtha_: 1jth A: [67270]
        Other proteins in same PDB: d1jthb_, d1jthd_
        complex with syntaxin fragments
      2. 1969185Domain d1jthc_: 1jth C: [67272]
        Other proteins in same PDB: d1jthb_, d1jthd_
        complex with syntaxin fragments
    2. Domains for 1n7s:
      1. 1969180Domain d1n7sc_: 1n7s C: [80273]
        Other proteins in same PDB: d1n7sa_, d1n7sb_
        complex with synaptobrevin and syntaxin fragments
        complexed with ca, mpd
      2. 1969181Domain d1n7sd_: 1n7s D: [80274]
        Other proteins in same PDB: d1n7sa_, d1n7sb_
        complex with synaptobrevin and syntaxin fragments
        complexed with ca, mpd
    3. Domains for 1sfc:
      1. 1969186Domain d1sfcc_: 1sfc C: [45645]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      2. 1969187Domain d1sfcd_: 1sfc D: [45646]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      3. 1969188Domain d1sfcg_: 1sfc G: [45649]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      4. 1969189Domain d1sfch_: 1sfc H: [45650]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      5. 1969190Domain d1sfck_: 1sfc K: [45653]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      6. 1969191Domain d1sfcl_: 1sfc L: [45654]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
    4. Domains for 1urq:
      1. 1969182Domain d1urqc_: 1urq C: [107996]
        Other proteins in same PDB: d1urqa_, d1urqb_
      2. 1969183Domain d1urqd_: 1urq D: [107997]
        Other proteins in same PDB: d1urqa_, d1urqb_

More info for Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex

Timeline for Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex: