SCOPe 2.08: Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM

Lineage for Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM [88786] (5 proteins)
   automatically mapped to Pfam PF00145

Proteins:

1. DNA methylase HaeIII [53371] (1 species)

   • Species Haemophilus aegyptius [TaxId:197575] [53372] (1 PDB entry)

2. DNA methylase HhaI [53367] (2 species)

   1. Species Haemophilus haemolyticus [TaxId:726] [53368] (16 PDB entries)
      Uniprot P05102

   2. Species Haemophilus parahaemolyticus [TaxId:735] [187136] (7 PDB entries)

3. DNMT2 [53375] (1 species)
   an enigmatic DNA methyltransferase homologue from mitochondria

   • Species Human (Homo sapiens) [TaxId:9606] [53376] (1 PDB entry)

4. Methyltransferase domain from DNA methyltransferase 1 (DNMT1) [267659] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [267738] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [267737] (4 PDB entries)

5. automated matches [190244] (3 species)
   not a true protein

   1. Species Haemophilus aegyptius [TaxId:197575] [194587] (1 PDB entry)

   2. Species Haemophilus haemolyticus [TaxId:726] [187017] (6 PDB entries)

   3. Species Haemophilus parahaemolyticus [TaxId:735] [188461] (1 PDB entry)

More info for Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM

Timeline for Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM:

• Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM first appeared in SCOP 1.65
  
• Family c.66.1.26: C5 cytosine-specific DNA methylase, DCM appears in SCOPe 2.07