SCOPe 2.07: Domain d1uaja1: 1uaj A:1-246

Lineage for d1uaja1 (1uaj A:1-246)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.116: alpha/beta knot [75216] (1 superfamily)
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot

4. Superfamily c.116.1: alpha/beta knot [75217] (9 families)
   known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
   all known members have dimeric structures

5. Family c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (2 proteins)
   fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain

6. Protein tRNA(m1G37)-methyltransferase TrmD [89630] (3 species)

7. Species Haemophilus influenzae [TaxId:727] [89631] (4 PDB entries)

8. Domain d1uaja1: 1uaj A:1-246 [88381]
   Other proteins in same PDB: d1uaja2

Details for d1uaja1

PDB Entry: 1uaj, 1.85 Å

PDB Description: Crystal structure of tRNA(m1G37)methyltransferase: Insight into tRNA recognition

PDB Compounds: (A:) tRNA (guanine-N(1)-)-methyltransferase

SCOPe Domain Sequences for d1uaja1:

Sequence, based on SEQRES records:

>d1uaja1 c.116.1.4 (A:1-246) tRNA(m1G37)-methyltransferase TrmD {Haemophilus influenzae [TaxId: 727]}
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfadglldcph
ytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkea
qaehns

Sequence, based on observed residues (ATOM records):

>d1uaja1 c.116.1.4 (A:1-246) tRNA(m1G37)-methyltransferase TrmD {Haemophilus influenzae [TaxId: 727]}
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlglldcphytrpevlegltvp
pvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkeaqaehns

Timeline for d1uaja1:

• d1uaja1 first appeared in SCOP 1.65, called d1uaja_
  
• d1uaja1 appears in SCOPe 2.06
  
• d1uaja1 appears in the current release, SCOPe 2.08