SCOPe 2.07: Domain d1oynd_: 1oyn D:

Lineage for d1oynd_ (1oyn D:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (72 PDB entries)
   Uniprot Q08499 388-713

8. Domain d1oynd_: 1oyn D: [87612]
   complexed with rol, zn

Details for d1oynd_

PDB Entry: 1oyn, 2 Å

PDB Description: Crystal structure of PDE4D2 in complex with (R,S)-rolipram

PDB Compounds: (D:) cAMP-specific phosphodiesterase PDE4D2

SCOPe Domain Sequences for d1oynd_:

Sequence; same for both SEQRES and ATOM records:

>d1oynd_ a.211.1.2 (D:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
iprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkip
vdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasa
ihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrq
slrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcad
lsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivh
plwetwadlvhpdaqdildtlednrewyqstipq

Timeline for d1oynd_:

• d1oynd_ first appeared in SCOP 1.65
  
• d1oynd_ appears in SCOPe 2.06
  
• d1oynd_ appears in the current release, SCOPe 2.08