SCOP 1.65: Domain d1oynd_: 1oyn D:

Lineage for d1oynd_ (1oyn D:)

1. Root: SCOP 1.65

2. Class a: All alpha proteins [46456] (179 folds)

3. Fold a.125: PDEase [48546] (1 superfamily)
   multihelical; can be divided into three subdomains

4. Superfamily a.125.1: PDEase [48547] (1 family)

5. Family a.125.1.1: PDEase [48548] (2 proteins)
   3',5'-cyclic-nucleotide phosphodiesterase, PF00233

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (3 PDB entries)

8. Domain d1oynd_: 1oyn D: [87612]
   complexed with rol, zn

Details for d1oynd_

PDB Entry: 1oyn, 2 Å

PDB Description: Crystal structure of PDE4D2 in complex with (R,S)-rolipram

SCOP Domain Sequences for d1oynd_:

Sequence; same for both SEQRES and ATOM records:

>d1oynd_ a.125.1.1 (D:) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens)}
iprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkip
vdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasa
ihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrq
slrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcad
lsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivh
plwetwadlvhpdaqdildtlednrewyqstipq

Timeline for d1oynd_:

• d1oynd_ is new in SCOP 1.65
  
• d1oynd_ appears in SCOP 1.67
  
• d1oynd_ appears in the current release, SCOPe 2.08