SCOPe 2.08: Domain d1nrvb_: 1nrv B:

Lineage for d1nrvb_ (1nrv B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flanked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Growth factor receptor-bound protein 10, GRB10 [89994] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89995] (1 PDB entry)

8. Domain d1nrvb_: 1nrv B: [86127]

Details for d1nrvb_

PDB Entry: 1nrv, 1.65 Å

PDB Description: Crystal structure of the SH2 domain of Grb10

PDB Compounds: (B:) Growth factor receptor-bound protein 10

SCOPe Domain Sequences for d1nrvb_:

Sequence, based on SEQRES records:

>d1nrvb_ d.93.1.1 (B:) Growth factor receptor-bound protein 10, GRB10 {Human (Homo sapiens) [TaxId: 9606]}
ihrtqhwfhgrisreeshriikqqglvdglfllrdsqsnpkafvltlchhqkiknfqilp
ceddgqtffslddgntkfsdliqlvdfyqlnkgvlpcklkhhcir

Sequence, based on observed residues (ATOM records):

>d1nrvb_ d.93.1.1 (B:) Growth factor receptor-bound protein 10, GRB10 {Human (Homo sapiens) [TaxId: 9606]}
ihrtqhwfhgrisreeshriikqqglvdglfllrdsqsnpkafvltlchhqkiknfqilp
ctffslddgntkfsdliqlvdfyqlnkgvlpcklkhhcir

Timeline for d1nrvb_:

• d1nrvb_ first appeared in SCOP 1.65
  
• d1nrvb_ appears in SCOPe 2.07