Lineage for Family a.64.1.3: Saposin B

1. Root: SCOP 1.63

2. Class a: All alpha proteins [46456] (171 folds)

3. Fold a.64: Saposin-like [47861] (2 superfamilies) 5 helices; folded leaf, closed

4. Superfamily a.64.1: Saposin [47862] (3 families) Lipid-binding can promote conformational changes and oligomerisation in some members

5. Family a.64.1.3: Saposin B [81806] (1 protein) the alternative subunit conformation is an open four-helical bundle; helices 3 and 4 form a contiguous helix