SCOPe 2.07: Domain d1lt7b_: 1lt7 B:

Lineage for d1lt7b_ (1lt7 B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.26: Homocysteine S-methyltransferase [82282] (1 family)

5. Family c.1.26.1: Homocysteine S-methyltransferase [82283] (3 proteins)
   Pfam PF02574

6. Protein Betaine-homocysteine S-methyltransferase [82284] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82285] (2 PDB entries)

8. Domain d1lt7b_: 1lt7 B: [78185]
   complexed with cit, sm

Details for d1lt7b_

PDB Entry: 1lt7, 2.15 Å

PDB Description: oxidized homo sapiens betaine-homocysteine s-methyltransferase in complex with four sm(iii) ions

PDB Compounds: (B:) betaine-homocysteine methyltransferase

SCOPe Domain Sequences for d1lt7b_:

Sequence, based on SEQRES records:

>d1lt7b_ c.1.26.1 (B:) Betaine-homocysteine S-methyltransferase {Human (Homo sapiens) [TaxId: 9606]}
kgilerlnageivigdggfvfalekrgyvkagpwtpeaavehpeavrqlhreflragsnv
mqtftfyasedklenrgnyvlekisgqevneaaadiarqvadegdalvaggvsqtpsyls
aksetevkkvflqqlevfmkknvdfliaeyfehveeavwavetliasgkpvaatmaigpe
gdlhgvppgeaavrlvkagasiigvnchfdptislktvklmkegleaaqlkahlmsqpla
yhtpdankqgfidlpefpfgleprvatrwdiqkyareaynlgvryiggccgfepyhirai
aeelapergflppasekhgswgsgldmhtkpwvrararkeywenlriasgrpynpsmskp
d

Sequence, based on observed residues (ATOM records):

>d1lt7b_ c.1.26.1 (B:) Betaine-homocysteine S-methyltransferase {Human (Homo sapiens) [TaxId: 9606]}
kgilerlnageivigdggfvfalekrgyhpeavrqlhreflragsnvmqtftvneaaadi
arqvadegdalvaggvsqtpsylsaksetevkkvflqqlevfmkknvdfliaeyfehvee
avwavetliasgkpvaatmaigpegdlhgvppgeaavrlvkagasiigvnchfdptislk
tvklmkegleaaqlkahlmsqplayhtpdankqgfidlpefpfgleprvatrwdiqkyar
eaynlgvryiggccgfepyhiraiaeelapergflppgldmhtkpwvrararkeywenlr
iasgrpynpsmskpd

Timeline for d1lt7b_:

• d1lt7b_ first appeared in SCOP 1.63
  
• d1lt7b_ appears in SCOPe 2.06
  
• d1lt7b_ appears in the current release, SCOPe 2.08