SCOPe 2.07: Family c.66.1.17: Spermidine synthase

Lineage for Family c.66.1.17: Spermidine synthase

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.17: Spermidine synthase [69557] (3 proteins)
   contains additional N-terminal tetramerisation all-beta domain, res. 1-71

Proteins:

1. Putative spermidine synthetase PF0127 (SpeE) [82479] (1 species)

   • Species Pyrococcus furiosus [TaxId:2261] [82480] (1 PDB entry)

2. Spermidine synthase [69558] (6 species)
   polyamine aminopropyltransferase

   1. Species Bacillus subtilis [TaxId:1423] [82478] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [142590] (5 PDB entries)
      Uniprot P19623 15-300

   3. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [142589] (1 PDB entry)
      Uniprot Q9U2F0 3-314

   4. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117680] (4 PDB entries)
      Uniprot Q9ZUB3

   5. Species Thermotoga maritima [TaxId:2336] [69559] (2 PDB entries)

   6. Species Thermus thermophilus [TaxId:274] [102586] (1 PDB entry)

3. automated matches [190432] (6 species)
   not a true protein

   1. Species Arabidopsis thaliana [TaxId:3702] [370997] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [189789] (1 PDB entry)

   3. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [187439] (1 PDB entry)

   4. Species Pyrococcus horikoshii OT3 [TaxId:70601] [187326] (1 PDB entry)

   5. Species Pyrococcus horikoshii [TaxId:53953] [188640] (1 PDB entry)

   6. Species Thermus thermophilus HB8 [TaxId:300852] [189902] (1 PDB entry)

More info for Family c.66.1.17: Spermidine synthase

Timeline for Family c.66.1.17: Spermidine synthase:

• Family c.66.1.17: Spermidine synthase first appeared in SCOP 1.59
  
• Family c.66.1.17: Spermidine synthase appears in SCOPe 2.06
  
• Family c.66.1.17: Spermidine synthase appears in the current release, SCOPe 2.08