SCOP 1.67: Domain d1h4ra2: 1h4r A:215-313

Lineage for d1h4ra2 (1h4r A:215-313)

1. Root: SCOP 1.67

2. Class b: All beta proteins [48724] (141 folds)

3. Fold b.55: PH domain-like [50728] (1 superfamily)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (8 families)

5. Family b.55.1.5: Third domain of FERM [50776] (6 proteins)

6. Protein Merlin [69294] (2 species)
   the neurofibromatosis 2 tumor suppressor protein

7. Species Human (Homo sapiens) [TaxId:9606] [69295] (1 PDB entry)

8. Domain d1h4ra2: 1h4r A:215-313 [65617]
   Other proteins in same PDB: d1h4ra1, d1h4ra3, d1h4rb1, d1h4rb3

Details for d1h4ra2

PDB Entry: 1h4r, 1.8 Å

PDB Description: crystal structure of the ferm domain of merlin, the neurofibromatosis 2 tumor suppressor protein.

SCOP Domain Sequences for d1h4ra2:

Sequence; same for both SEQRES and ATOM records:

>d1h4ra2 b.55.1.5 (A:215-313) Merlin {Human (Homo sapiens)}
emygvnyfairnkkgtelllgvdalglhiydpenrltpkisfpwneirnisysdkeftik
pldkkidvfkfnssklrvnklilqlcignhdlfmrrrka

Timeline for d1h4ra2:

• d1h4ra2 first appeared in SCOP 1.59
  
• d1h4ra2 appears in SCOP 1.65
  
• d1h4ra2 appears in SCOP 1.69
  
• d1h4ra2 appears in the current release, SCOPe 2.08