Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1843167Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 1843168Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 1843434Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 1843488Protein Sirt2 histone deacetylase [63987] (1 species)
  7. 1843489Species Human (Homo sapiens) [TaxId:9606] [63988] (1 PDB entry)

PDB entry in Species: Human (Homo sapiens) [TaxId: 9606]:

More info for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase: