Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2444630Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2444631Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2444911Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 protein domains)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2444971Protein Sirt2 histone deacetylase [63987] (1 species)
  7. 2444972Species Human (Homo sapiens) [TaxId:9606] [63988] (15 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1j8f:
    1. 2444974Domain d1j8fa_: 1j8f A: [62738]
      complexed with zn
    2. 2444975Domain d1j8fb_: 1j8f B: [62739]
      complexed with zn
    3. 2444976Domain d1j8fc_: 1j8f C: [62740]
      complexed with zn
  2. Domain(s) for 4rmg:
  3. Domain(s) for 4rmh:
  4. Domain(s) for 4rmi:
  5. Domain(s) for 4rmj:
    1. 2444981Domain d4rmja1: 4rmj A:56-355 [269352]
      Other proteins in same PDB: d4rmja2, d4rmjb2
      automated match to d1j8fc_
      complexed with ar6, edo, na, nca, peg, pge, zn
    2. 2444982Domain d4rmjb1: 4rmj B:56-355 [269356]
      Other proteins in same PDB: d4rmja2, d4rmjb2
      automated match to d1j8fc_
      complexed with ar6, edo, na, nca, peg, pge, zn
  6. Domain(s) for 4y6q:
    1. 2444988Domain d4y6qa_: 4y6q A: [310100]
      automated match to d1j8fc_
      complexed with omr, zn
    2. 2444989Domain d4y6qb_: 4y6q B: [310101]
      automated match to d1j8fc_
      complexed with omr, zn
    3. 2444990Domain d4y6qc_: 4y6q C: [310102]
      automated match to d1j8fc_
      complexed with omr, zn
    4. 2444991Domain d4y6qd_: 4y6q D: [310103]
      automated match to d1j8fc_
      complexed with omr, zn
  7. Domain(s) for 5d7o:
    1. 2444978Domain d5d7oa_: 5d7o A: [310390]
      automated match to d5dy4a_
      complexed with ar6, pge, zn
    2. 2444979Domain d5d7ob_: 5d7o B: [310391]
      automated match to d5dy4a_
      complexed with ar6, pge, zn
  8. Domain(s) for 5d7p:
    1. 2444983Domain d5d7pa1: 5d7p A:56-355 [310392]
      Other proteins in same PDB: d5d7pa2
      automated match to d5dy4a_
      complexed with ar6, ocz, peg, zn
    2. 2444984Domain d5d7pb_: 5d7p B: [310394]
      Other proteins in same PDB: d5d7pa2
      automated match to d5dy4a_
      complexed with ar6, ocz, peg, zn
  9. Domain(s) for 5d7q:
    1. 2444993Domain d5d7qa1: 5d7q A:56-354 [310395]
      Other proteins in same PDB: d5d7qa2
      automated match to d5dy4a_
      complexed with 4i5, ar6, zn
    2. 2444994Domain d5d7qb_: 5d7q B: [310397]
      Other proteins in same PDB: d5d7qa2
      automated match to d5dy4a_
      complexed with 4i5, ar6, zn
  10. Domain(s) for 5dy4:
  11. Domain(s) for 5dy5:
  12. Domain(s) for 5g4c:
    1. 2444997Domain d5g4ca_: 5g4c A: [333699]
      automated match to d1j8fa_
      complexed with cna, zn
    2. 2444998Domain d5g4cb_: 5g4c B: [333716]
      automated match to d1j8fa_
      complexed with cna, zn
  13. Domain(s) for 5mar:
    1. 2444986Domain d5mara1: 5mar A:56-355 [331104]
      Other proteins in same PDB: d5mara2, d5marb2
      automated match to d4rmha_
      complexed with 7ke, act, ar6, dms, edo, gol, zn
    2. 2444987Domain d5marb1: 5mar B:56-355 [331084]
      Other proteins in same PDB: d5mara2, d5marb2
      automated match to d4rmha_
      complexed with 7ke, act, ar6, dms, edo, gol, zn
  14. Domain(s) for 5mat:
    1. 2444995Domain d5mata1: 5mat A:56-356 [329544]
      Other proteins in same PDB: d5mata2, d5matc2
      automated match to d4rmha_
      complexed with 7kj, p6g, pg4, so4, zn
    2. 2444996Domain d5matc1: 5mat C:56-356 [329582]
      Other proteins in same PDB: d5mata2, d5matc2
      automated match to d4rmha_
      complexed with 7kj, p6g, pg4, so4, zn
  15. Domain(s) for 5y5n:

More info for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase: