Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2121033Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2121034Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2121318Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2121378Protein Sirt2 histone deacetylase [63987] (1 species)
  7. 2121379Species Human (Homo sapiens) [TaxId:9606] [63988] (3 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1j8f:
    1. 2121380Domain d1j8fa_: 1j8f A: [62738]
      complexed with zn
    2. 2121381Domain d1j8fb_: 1j8f B: [62739]
      complexed with zn
    3. 2121382Domain d1j8fc_: 1j8f C: [62740]
      complexed with zn
  2. Domain(s) for 5g4c:
    1. 2121383Domain d5g4ca_: 5g4c A: [333699]
      automated match to d1j8fa_
      complexed with cna, zn
    2. 2121384Domain d5g4cb_: 5g4c B: [333716]
      automated match to d1j8fa_
      complexed with cna, zn
  3. Domain(s) for 5y5n:

More info for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 Sirt2 histone deacetylase: