SCOP 1.75: Domain d1i2ra_: 1i2r A:

Lineage for d1i2ra_ (1i2r A:)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (8 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (12 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein Transaldolase [51588] (3 species)
   probably related to class I aldolases by a circular permutation

7. Species Escherichia coli [TaxId:562] [51589] (7 PDB entries)

8. Domain d1i2ra_: 1i2r A: [61580]

Details for d1i2ra_

PDB Entry: 1i2r, 2.1 Å

PDB Description: crystal structure of escherichia coli transaldolase b mutant s176a

PDB Compounds: (A:) transaldolase b

SCOP Domain Sequences for d1i2ra_:

Sequence; same for both SEQRES and ATOM records:

>d1i2ra_ c.1.10.1 (A:) Transaldolase {Escherichia coli [TaxId: 562]}
tdkltslrqyttvvadtgdiaamklyqpqdattnpslilnaaqipeyrkliddavawakq
qsndraqqivdatdklavnigleilklvpgristevdarlsydteasiakakrliklynd
agisndriliklastwqgiraaeqlekegincnltllfsfaqaracaeagvfliapfvgr
ildwykantdkkeyapaedpgvvsvseiyqyykehgyetvvmgasfrnigeilelagcdr
ltiapallkelaesegaierklsytgevkarpariteseflwqhnqdpmavdklaegirk
faidqeklekmigdll

Timeline for d1i2ra_:

• d1i2ra_ first appeared in SCOP 1.57
  
• d1i2ra_ appears in SCOP 1.73
  
• d1i2ra_ appears in SCOPe 2.01
  
• d1i2ra_ appears in the current release, SCOPe 2.08