SCOPe 2.04: Domain d1f45a2: 1f45 A:88-211

Lineage for d1f45a2 (1f45 A:88-211)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.2: Fibronectin type III [49265] (2 families)

5. Family b.1.2.1: Fibronectin type III [49266] (45 proteins)
   Pfam PF00041

6. Protein The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63673] (5 PDB entries)

8. Domain d1f45a2: 1f45 A:88-211 [59640]
   Other proteins in same PDB: d1f45a1, d1f45b_

Details for d1f45a2

PDB Entry: 1f45, 2.8 Å

PDB Description: human interleukin-12

PDB Compounds: (A:) interleukin-12 beta chain

SCOPe Domain Sequences for d1f45a2:

Sequence, based on SEQRES records:

>d1f45a2 b.1.2.1 (A:88-211) The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 {Human (Homo sapiens) [TaxId: 9606]}
giwstdilkdqkepknktflrceaknysgrftcwwlttistdltfsvkssrgssdpqgvt
cgaatlsaervrgdnkeyeysvecqedsacpaaeeslpievmvdavhklkyenytssffi
rdii

Sequence, based on observed residues (ATOM records):

>d1f45a2 b.1.2.1 (A:88-211) The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 {Human (Homo sapiens) [TaxId: 9606]}
giwstdilkdqkepknktflrceaknysgrftcwwlttistdltfsvkssrgssdpqgvt
cgaatlsaeeyeysvecqedsacpaaeeslpievmvdavhklkyenytssffirdii

Timeline for d1f45a2:

• d1f45a2 first appeared in SCOP 1.57
  
• d1f45a2 appears in SCOPe 2.03
  
• d1f45a2 appears in SCOPe 2.05
  
• d1f45a2 appears in the current release, SCOPe 2.08