Lineage for Superfamily e.10.1: Prokaryotic type I DNA topoisomerase

  1. Root: SCOP 1.63
  2. 266016Class e: Multi-domain proteins (alpha and beta) [56572] (39 folds)
  3. 266966Fold e.10: Prokaryotic type I DNA topoisomerase [56711] (1 superfamily)
    4 domains: (1) Toprim alpha/beta; (2&4) "winged helix"-like; (3) barrel: n=6, S=8
  4. 266967Superfamily e.10.1: Prokaryotic type I DNA topoisomerase [56712] (1 family) (S)
    duplication: the protein chain passing through the domains 2-4 makes two structural repeats
    The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV

Family:

More info for Superfamily e.10.1: Prokaryotic type I DNA topoisomerase

Timeline for Superfamily e.10.1: Prokaryotic type I DNA topoisomerase: