SCOPe 2.03: Protein: Phoshoinositide 3-kinase (PI3K), catalytic domain

Lineage for Protein: Phoshoinositide 3-kinase (PI3K), catalytic domain

Root: SCOPe 2.03
Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain [56171] (1 protein)
Protein Phoshoinositide 3-kinase (PI3K), catalytic domain [56172] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [56174] (19 PDB entries)
1. Domain for 1e8y:
  - Domain d1e8ya4: 1e8y A:726-1092 [41715]
    Other proteins in same PDB: d1e8ya1, d1e8ya2, d1e8ya3
2. Domain for 1e8z:
  - Domain d1e8za4: 1e8z A:726-1092 [41716]
    Other proteins in same PDB: d1e8za1, d1e8za2, d1e8za3
    complexed with stu
3. Domain for 1he8:
  - Domain d1he8a4: 1he8 A:726-1084 [41717]
    Other proteins in same PDB: d1he8a1, d1he8a2, d1he8a3, d1he8b_
    complexed with gnp, mg
4. Domain for 2a4z:
  - Domain d2a4za4: 2a4z A:726-1087 [203393]
    Other proteins in same PDB: d2a4za1, d2a4za2, d2a4za3
    automated match to d1e8ya4
    complexed with bym
5. Domain for 2a5u:
  - Domain d2a5ua4: 2a5u A:726-1092 [203397]
    Other proteins in same PDB: d2a5ua1, d2a5ua2, d2a5ua3
    automated match to d1e8ya4
    complexed with qyt
6. Domain for 2chw:
  - Domain d2chwa4: 2chw A:726-1092 [203790]
    Other proteins in same PDB: d2chwa1, d2chwa2, d2chwa3
    automated match to d1e8ya4
    complexed with 039
7. Domain for 2chx:
  - Domain d2chxa4: 2chx A:726-1093 [203794]
    Other proteins in same PDB: d2chxa1, d2chxa2, d2chxa3
    automated match to d1e8ya4
    complexed with 090
8. Domain for 2chz:
  - Domain d2chza4: 2chz A:726-1093 [203798]
    Other proteins in same PDB: d2chza1, d2chza2, d2chza3
    automated match to d1e8ya4
    complexed with 093
9. Domain for 2v4l:
  - Domain d2v4la4: 2v4l A:726-1093 [206206]
    Other proteins in same PDB: d2v4la1, d2v4la2, d2v4la3
    automated match to d1e8ya4
    complexed with abj
10. Domain for 3dpd:
  - Domain d3dpda4: 3dpd A:726-1094 [209253]
    Other proteins in same PDB: d3dpda1, d3dpda2, d3dpda3
    automated match to d1e8ya4
    complexed with 41a
11. Domain for 3ibe:
  - Domain d3ibea4: 3ibe A:726-1092 [211568]
    Other proteins in same PDB: d3ibea1, d3ibea2, d3ibea3
    automated match to d1e8ya4
    complexed with l64, so4
12. Domain for 3lj3:
  - Domain d3lj3a4: 3lj3 A:726-1090 [212908]
    Other proteins in same PDB: d3lj3a1, d3lj3a2, d3lj3a3
    automated match to d1e8ya4
    complexed with so4, wye
13. Domain for 3mjw:
  - Domain d3mjwa4: 3mjw A:726-1089 [213289]
    Other proteins in same PDB: d3mjwa1, d3mjwa2, d3mjwa3
    automated match to d1e8ya4
    complexed with wyf
14. Domain for 3ml8:
  - Domain d3ml8a4: 3ml8 A:726-1093 [213321]
    Other proteins in same PDB: d3ml8a1, d3ml8a2, d3ml8a3
    automated match to d1e8ya4
    complexed with ml8
15. Domain for 3ml9:
  - Domain d3ml9a4: 3ml9 A:726-1093 [213325]
    Other proteins in same PDB: d3ml9a1, d3ml9a2, d3ml9a3
    automated match to d1e8ya4
    complexed with ml9
16. Domain for 3tjp:
  - Domain d3tjpa4: 3tjp A:726-1093 [216845]
    Other proteins in same PDB: d3tjpa1, d3tjpa2, d3tjpa3
    automated match to d1e8ya4
    complexed with 13k, so4
17. Domain for 4ful:
  - Domain d4fula4: 4ful A:726-1092 [221538]
    Other proteins in same PDB: d4fula1, d4fula2, d4fula3
    automated match to d1e8ya4
    complexed with 0vu
18. Domain for 4hvb:
  - Domain d4hvba4: 4hvb A:726-1090 [229092]
    Other proteins in same PDB: d4hvba1, d4hvba2, d4hvba3
    automated match to d1e8ya4
    complexed with 19p
19. Domain for 4kz0:
  - Domain d4kz0a4: 4kz0 A:726-1092 [224532]
    Other proteins in same PDB: d4kz0a1, d4kz0a2, d4kz0a3
    automated match to d1e8ya4
    complexed with 1uj, so4
Pig (Sus scrofa) [TaxId:9823] [56173] (5 PDB entries)
1. Domain for 1e7u:
  - Domain d1e7ua4: 1e7u A:726-1094 [41710]
    Other proteins in same PDB: d1e7ua1, d1e7ua2, d1e7ua3
    complexed with kwt
2. Domain for 1e7v:
  - Domain d1e7va4: 1e7v A:726-1094 [41712]
    Other proteins in same PDB: d1e7va1, d1e7va2, d1e7va3
    complexed with ly2
3. Domain for 1e8w:
  - Domain d1e8wa4: 1e8w A:726-1094 [41714]
    Other proteins in same PDB: d1e8wa1, d1e8wa2, d1e8wa3
    complexed with que
4. Domain for 1e8x:
  - Domain d1e8xa4: 1e8x A:726-1092 [41711]
    Other proteins in same PDB: d1e8xa1, d1e8xa2, d1e8xa3
    complexed with atp, lu
5. Domain for 1e90:
  - Domain d1e90a4: 1e90 A:726-1094 [41713]
    Other proteins in same PDB: d1e90a1, d1e90a2, d1e90a3
    complexed with myc

More info for Protein Phoshoinositide 3-kinase (PI3K), catalytic domain from d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain

Timeline for Protein Phoshoinositide 3-kinase (PI3K), catalytic domain from d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain:

Protein Phoshoinositide 3-kinase (PI3K), catalytic domain from d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain first appeared (with stable ids) in SCOP 1.55
Protein Phoshoinositide 3-kinase (PI3K), catalytic domain from d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain appears in SCOPe 2.02
Protein Phoshoinositide 3-kinase (PI3K), catalytic domain from d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain appears in SCOPe 2.04
Protein Phoshoinositide 3-kinase (PI3K), catalytic domain from d.144.1.4: Phoshoinositide 3-kinase (PI3K), catalytic domain appears in the current release, SCOPe 2.08