SCOPe 2.02: Family d.109.1.2: Cofilin-like

Lineage for Family d.109.1.2: Cofilin-like

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.109: Gelsolin-like [55752] (3 superfamilies)
   3 layers: a/b/a; contains mixed beta-sheet

4. Superfamily d.109.1: Actin depolymerizing proteins [55753] (3 families)

5. Family d.109.1.2: Cofilin-like [55762] (8 proteins)

Proteins:

1. Adf-H domain of twinfilin isoform-1 [82752] (1 species)
   interacts only with G-actin

   • Species Mouse (Mus musculus) [TaxId:10090] [82753] (1 PDB entry)

2. Coactosin-like protein Cotl1 (Clp) [111105] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [111107] (2 PDB entries)
      Uniprot Q14019

   2. Species Mouse (Mus musculus) [TaxId:10090] [111106] (2 PDB entries)
      Uniprot Q9CQI6

3. Cofilin (actin depolymerizing factor, ADF) [55763] (4 species)

   1. Species Acanthamoeba castellanii, actophorin [TaxId:5755] [55766] (2 PDB entries)

   2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55765] (3 PDB entries)

   3. Species Human (Homo sapiens), non-muscle isoform [TaxId:9606] [111104] (2 PDB entries)
      Uniprot P23528

   4. Species Plant (Arabidopsis thaliana), ADF1 [TaxId:3702] [55764] (1 PDB entry)

4. Cofilin-like domain of actin-binding protein abp1p [69793] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69794] (1 PDB entry)

5. Destrin [55767] (1 species)

   • Species Human and pig (Homo sapiens) and (Sus scrofa) [TaxId:9606] [55768] (2 PDB entries)
     identical sequence in both species

6. Glia maturation factor beta, GMF-beta [111108] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [111109] (1 PDB entry)
     Uniprot Q9CQI3

7. Glia maturation factor gamma, GMF-gamma [111110] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [189226] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [111111] (2 PDB entries)
      Uniprot Q9ERL7

8. automated matches [190045] (3 species)
   not a true protein

   1. Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [187836] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [186766] (4 PDB entries)

   3. Species Saccharomyces cerevisiae [TaxId:559292] [197113] (2 PDB entries)

More info for Family d.109.1.2: Cofilin-like

Timeline for Family d.109.1.2: Cofilin-like:

• Family d.109.1.2: Cofilin-like first appeared (with stable ids) in SCOP 1.55
  
• Family d.109.1.2: Cofilin-like appears in SCOPe 2.01
  
• Family d.109.1.2: Cofilin-like appears in SCOPe 2.03
  
• Family d.109.1.2: Cofilin-like appears in the current release, SCOPe 2.08