Lineage for Family d.109.1.2: Cofilin-like

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.109: Gelsolin-like [55752] (3 superfamilies)
    3 layers: a/b/a; contains mixed beta-sheet
  4. Superfamily d.109.1: Actin depolymerizing proteins [55753] (3 families) (S)
  5. Family d.109.1.2: Cofilin-like [55762] (8 proteins)

Proteins:

  1. Adf-H domain of twinfilin isoform-1 [82752] (1 species)
    interacts only with G-actin
  2. Coactosin-like protein Cotl1 (Clp) [111105] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [111107] (2 PDB entries)
      Uniprot Q14019
    2. Species Mouse (Mus musculus) [TaxId:10090] [111106] (2 PDB entries)
      Uniprot Q9CQI6
  3. Cofilin (actin depolymerizing factor, ADF) [55763] (4 species)
    1. Species Acanthamoeba castellanii, actophorin [TaxId:5755] [55766] (2 PDB entries)
    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55765] (3 PDB entries)
    3. Species Human (Homo sapiens), non-muscle isoform [TaxId:9606] [111104] (3 PDB entries)
      Uniprot P23528
    4. Species Thale cress (Arabidopsis thaliana), ADF1 [TaxId:3702] [55764] (1 PDB entry)
  4. Cofilin-like domain of actin-binding protein abp1p [69793] (1 species)
  5. Destrin [55767] (1 species)
  6. Glia maturation factor beta, GMF-beta [111108] (1 species)
  7. Glia maturation factor gamma, GMF-gamma [111110] (2 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [189226] (1 PDB entry)
    2. Species Mouse (Mus musculus) [TaxId:10090] [111111] (2 PDB entries)
      Uniprot Q9ERL7
  8. automated matches [190045] (5 species)
    not a true protein
    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [197113] (3 PDB entries)
    2. Species Chicken (Gallus gallus) [TaxId:9031] [254904] (1 PDB entry)
    3. Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [187836] (1 PDB entry)
    4. Species Human (Homo sapiens) [TaxId:9606] [186766] (6 PDB entries)
    5. Species Mouse (Mus musculus) [TaxId:10090] [256328] (1 PDB entry)

More info for Family d.109.1.2: Cofilin-like

Timeline for Family d.109.1.2: Cofilin-like: