SCOPe 2.03: Protein: Phoshoinositide 3-kinase (PI3K)

Lineage for Protein: Phoshoinositide 3-kinase (PI3K)

Root: SCOPe 2.03
Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
Fold d.15: beta-Grasp (ubiquitin-like) [54235] (14 superfamilies)
core: beta(2)-alpha-beta(2); mixed beta-sheet 2143
Superfamily d.15.1: Ubiquitin-like [54236] (9 families)
Family d.15.1.5: Ras-binding domain, RBD [54263] (14 proteins)
contains Pfam PF00788 and Pfam PF02196
Protein Phoshoinositide 3-kinase (PI3K) [54274] (2 species)
includes parts of the flanking linkers

Species:

Human (Homo sapiens) [TaxId:9606] [54276] (19 PDB entries)
1. Domain for 1e8y:
  - Domain d1e8ya3: 1e8y A:143-322 [37635]
    Other proteins in same PDB: d1e8ya1, d1e8ya2, d1e8ya4
2. Domain for 1e8z:
  - Domain d1e8za3: 1e8z A:144-322 [37636]
    Other proteins in same PDB: d1e8za1, d1e8za2, d1e8za4
    complexed with stu
3. Domain for 1he8:
  - Domain d1he8a3: 1he8 A:144-321 [37637]
    Other proteins in same PDB: d1he8a1, d1he8a2, d1he8a4, d1he8b_
    complexed with gnp, mg
4. Domain for 2a4z:
  - Domain d2a4za1: 2a4z A:144-321 [203390]
    Other proteins in same PDB: d2a4za2, d2a4za3, d2a4za4
    automated match to d1e8ya3
    complexed with bym
5. Domain for 2a5u:
  - Domain d2a5ua1: 2a5u A:144-322 [203394]
    Other proteins in same PDB: d2a5ua2, d2a5ua3, d2a5ua4
    automated match to d1e8ya3
    complexed with qyt
6. Domain for 2chw:
  - Domain d2chwa1: 2chw A:144-322 [203787]
    Other proteins in same PDB: d2chwa2, d2chwa3, d2chwa4
    automated match to d1e8ya3
    complexed with 039
7. Domain for 2chx:
  - Domain d2chxa1: 2chx A:144-322 [203791]
    Other proteins in same PDB: d2chxa2, d2chxa3, d2chxa4
    automated match to d1e8ya3
    complexed with 090
8. Domain for 2chz:
  - Domain d2chza1: 2chz A:144-322 [203795]
    Other proteins in same PDB: d2chza2, d2chza3, d2chza4
    automated match to d1e8ya3
    complexed with 093
9. Domain for 2v4l:
  - Domain d2v4la1: 2v4l A:144-322 [206203]
    Other proteins in same PDB: d2v4la2, d2v4la3, d2v4la4
    automated match to d1e8ya3
    complexed with abj
10. Domain for 3dpd:
  - Domain d3dpda1: 3dpd A:143-321 [209250]
    Other proteins in same PDB: d3dpda2, d3dpda3, d3dpda4
    automated match to d1e8ya3
    complexed with 41a
11. Domain for 3ibe:
  - Domain d3ibea1: 3ibe A:143-322 [211565]
    Other proteins in same PDB: d3ibea2, d3ibea3, d3ibea4
    automated match to d1e8ya3
    complexed with l64, so4
12. Domain for 3lj3:
  - Domain d3lj3a1: 3lj3 A:143-321 [212905]
    Other proteins in same PDB: d3lj3a2, d3lj3a3, d3lj3a4
    automated match to d1e8ya3
    complexed with so4, wye
13. Domain for 3mjw:
  - Domain d3mjwa1: 3mjw A:143-321 [213286]
    Other proteins in same PDB: d3mjwa2, d3mjwa3, d3mjwa4
    automated match to d1e8ya3
    complexed with wyf
14. Domain for 3ml8:
  - Domain d3ml8a1: 3ml8 A:144-322 [213318]
    Other proteins in same PDB: d3ml8a2, d3ml8a3, d3ml8a4
    automated match to d1e8ya3
    complexed with ml8
15. Domain for 3ml9:
  - Domain d3ml9a1: 3ml9 A:144-321 [213322]
    Other proteins in same PDB: d3ml9a2, d3ml9a3, d3ml9a4
    automated match to d1e8ya3
    complexed with ml9
16. Domain for 3tjp:
  - Domain d3tjpa1: 3tjp A:144-321 [216842]
    Other proteins in same PDB: d3tjpa2, d3tjpa3, d3tjpa4
    automated match to d1e8ya3
    complexed with 13k, so4
17. Domain for 4ful:
  - Domain d4fula1: 4ful A:145-321 [221535]
    Other proteins in same PDB: d4fula2, d4fula3, d4fula4
    automated match to d1e8ya3
    complexed with 0vu
18. Domain for 4hvb:
  - Domain d4hvba1: 4hvb A:144-322 [229089]
    Other proteins in same PDB: d4hvba2, d4hvba3, d4hvba4
    automated match to d1e8ya3
    complexed with 19p
19. Domain for 4kz0:
  - Domain d4kz0a1: 4kz0 A:144-322 [224529]
    Other proteins in same PDB: d4kz0a2, d4kz0a3, d4kz0a4
    automated match to d1e8ya3
    complexed with 1uj, so4
Pig (Sus scrofa) [TaxId:9823] [54275] (5 PDB entries)
1. Domain for 1e7u:
  - Domain d1e7ua3: 1e7u A:143-321 [37630]
    Other proteins in same PDB: d1e7ua1, d1e7ua2, d1e7ua4
    complexed with kwt
2. Domain for 1e7v:
  - Domain d1e7va3: 1e7v A:143-321 [37632]
    Other proteins in same PDB: d1e7va1, d1e7va2, d1e7va4
    complexed with ly2
3. Domain for 1e8w:
  - Domain d1e8wa3: 1e8w A:143-321 [37634]
    Other proteins in same PDB: d1e8wa1, d1e8wa2, d1e8wa4
    complexed with que
4. Domain for 1e8x:
  - Domain d1e8xa3: 1e8x A:142-321 [37631]
    Other proteins in same PDB: d1e8xa1, d1e8xa2, d1e8xa4
    complexed with atp, lu
5. Domain for 1e90:
  - Domain d1e90a3: 1e90 A:143-321 [37633]
    Other proteins in same PDB: d1e90a1, d1e90a2, d1e90a4
    complexed with myc

More info for Protein Phoshoinositide 3-kinase (PI3K) from d.15.1.5: Ras-binding domain, RBD

Timeline for Protein Phoshoinositide 3-kinase (PI3K) from d.15.1.5: Ras-binding domain, RBD:

Protein Phoshoinositide 3-kinase (PI3K) from d.15.1.5: Ras-binding domain, RBD first appeared (with stable ids) in SCOP 1.55
Protein Phoshoinositide 3-kinase (PI3K) from d.15.1.5: Ras-binding domain, RBD appears in SCOPe 2.02
Protein Phoshoinositide 3-kinase (PI3K) from d.15.1.5: Ras-binding domain, RBD appears in SCOPe 2.04
Protein Phoshoinositide 3-kinase (PI3K) from d.15.1.5: Ras-binding domain, RBD appears in the current release, SCOPe 2.08