Lineage for Superfamily c.50.1: Macro domain-like

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2459390Fold c.50: Macro domain-like [52948] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest
  4. 2459391Superfamily c.50.1: Macro domain-like [52949] (4 families) (S)

Families:

  1. 2459392c.50.1.1: Leucine aminopeptidase (Aminopeptidase A), N-terminal domain [52950] (1 protein)
  2. 2459416c.50.1.2: Macro domain [89724] (7 protein domains)
    found in different proteins, including macro-H2a histone and the Appr-1"-p processing enzyme
  3. 2459514c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like [310642] (2 protein domains)
    Pfam PF05028
    Contains N- and C-terminal extensions to macrodomain, including Tyr clasp, discussed in PubMed 22609859
  4. 2459548c.50.1.0: automated matches [191326] (1 protein)
    not a true family

More info for Superfamily c.50.1: Macro domain-like

Timeline for Superfamily c.50.1: Macro domain-like: