SCOPe 2.08: Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like

Lineage for Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.50: Macro domain-like [52948] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest

4. Superfamily c.50.1: Macro domain-like [52949] (4 families)

5. Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like [310642] (2 proteins)
   Pfam PF05028
   Contains N- and C-terminal extensions to macrodomain, including Tyr clasp, discussed in PubMed 22609859

Proteins:

1. Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain [310785] (3 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [324080] (19 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [311376] (7 PDB entries)

   3. Species Norway rat (Rattus norvegicus) [TaxId:10116] [311041] (2 PDB entries)

2. automated matches [310881] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [311355] (6 PDB entries)

More info for Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like

Timeline for Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like:

• Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like first appeared in SCOPe 2.06
  
• Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like appears in SCOPe 2.07