Lineage for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 242562Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 242563Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (5 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 242581Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (4 proteins)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold

Proteins:

  1. 242582Acetohydroxyacid synthase catalytic subunit [69463] (1 species)
  2. 242588Benzoylformate decarboxylase [52482] (1 species)
  3. 242607Pyruvate decarboxylase [52478] (3 species)
    rudiment domain with a variant fold, lacks FAD-binding
    1. 242608Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52480] (2 PDB entries)
    2. 242613Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [52479] (1 PDB entry)
    3. 242616Species Zymomonas mobilis [TaxId:542] [52481] (1 PDB entry)
  4. 242621Pyruvate oxidase [52476] (1 species)
    binds FAD

More info for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain: