SCOPe 2.08: Family c.23.16.2: DJ-1/PfpI

Lineage for Family c.23.16.2: DJ-1/PfpI

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
   3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345

4. Superfamily c.23.16: Class I glutamine amidotransferase-like [52317] (10 families)
   conserved positions of the oxyanion hole and catalytic nucleophile; different constituent families contain different additional structures

5. Family c.23.16.2: DJ-1/PfpI [52325] (10 proteins)
   contains a catalytic triad or dyad different from the class I GAT triad

Proteins:

1. DJ-1 [89603] (1 species)
   RNA-binding protein regulatory subunit

   • Species Human (Homo sapiens) [TaxId:9606] [89604] (62 PDB entries)
     Uniprot Q99497

2. GK2698 ortholog [117481] (1 species)

   • Species Bacillus stearothermophilus [TaxId:1422] [117482] (1 PDB entry)
     Uniprot Q5KWF3; 96% sequence identity; Geobacillus kaustophilus TaxID: 1462

3. HSP31 (HchA; YedU) [89609] (1 species)
   contains a buried Cys-His-Asp triad within one subunit

   • Species Escherichia coli [TaxId:562] [89610] (5 PDB entries)

4. Hypothetical protein Atu0886 [142072] (1 species)

   • Species Agrobacterium tumefaciens [TaxId:358] [142073] (1 PDB entry)
     Uniprot Q8UGZ9 1-188

5. Hypothetical protein Ydr533Cp [102253] (1 species)
   contains a buried Cys-His-Glu triad within one subunit

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [102254] (4 PDB entries)

6. Hypothetical protein YhbO [89601] (1 species)

   • Species Escherichia coli [TaxId:562] [89602] (1 PDB entry)

7. Intracellular protease [52326] (3 species)

   1. Species Pyrococcus furiosus [TaxId:2261] [419776] (1 PDB entry)

   2. Species Pyrococcus horikoshii [TaxId:53953] [52327] (3 PDB entries)

   3. Species Pyrococcus horikoshii [TaxId:70601] [370077] (1 PDB entry)

8. Protein ThiJ (YajL) [142070] (1 species)

   • Species Escherichia coli [TaxId:562] [142071] (1 PDB entry)
     Uniprot Q46948 2-196

9. Putative sigma cross-reacting protein 27A (SCRP-27A, EllB) [89606] (1 species)
   involved in an early stage of isoprenoid biosynthesis; contains a Cys-Glu putative catalytic dyad

   • Species Escherichia coli [TaxId:562] [89607] (2 PDB entries)

10. automated matches [190995] (8 species)
    not a true protein

    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [258813] (1 PDB entry)

    2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189556] (1 PDB entry)

    3. Species Candida albicans [TaxId:237561] [226745] (1 PDB entry)

    4. Species Escherichia coli [TaxId:562] [327688] (1 PDB entry)

    5. Species Human (Homo sapiens) [TaxId:9606] [188709] (1 PDB entry)

    6. Species Salmonella enterica [TaxId:90371] [322712] (1 PDB entry)

    7. Species Thermococcus onnurineus [TaxId:523850] [189567] (1 PDB entry)

    8. Species Thermococcus thioreducens [TaxId:277988] [338977] (2 PDB entries)

More info for Family c.23.16.2: DJ-1/PfpI

Timeline for Family c.23.16.2: DJ-1/PfpI:

• Family c.23.16.2: DJ-1/PfpI first appeared (with stable ids) in SCOP 1.55, called Family c.23.16.2: Intracellular protease
  
• Family c.23.16.2: DJ-1/PfpI appears in SCOPe 2.07