SCOPe 2.06: Family b.60.1.2: Fatty acid binding protein-like

Lineage for Family b.60.1.2: Fatty acid binding protein-like

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.60: Lipocalins [50813] (1 superfamily)
   barrel, closed or opened; n=8, S=12; meander

4. Superfamily b.60.1: Lipocalins [50814] (10 families)
   bind hydrophobic ligands in their interior

5. Family b.60.1.2: Fatty acid binding protein-like [50847] (18 proteins)
   ten-stranded meander beta-sheet folded upon itself
   relates to the common fold by opening the barrel and insertion of beta-hairpin

Proteins:

1. Adipocyte lipid-binding protein, ALBP [50856] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [110275] (17 PDB entries)
      Uniprot P15090

   2. Species Mouse (Mus musculus) [TaxId:10090] [50857] (21 PDB entries)

2. Brain fatty acid binding protein [63809] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [63810] (3 PDB entries)

3. Cellular retinoic-acid-binding protein (CRABP) [50861] (2 species)

   1. Species Cow and mouse (Bos taurus) and (Mus musculus), CRABP-I, identical sequences [TaxId:9913] [50863] (3 PDB entries)

   2. Species Human (Homo sapiens), CRABP-II [TaxId:9606] [50862] (52 PDB entries)

4. Cellular retinol-binding protein II (CRBP) [50864] (2 species)

   1. Species Norway rat (Rattus norvegicus) [TaxId:10116] [50865] (9 PDB entries)

   2. Species Zebrafish (Danio rerio) [TaxId:7955] [75000] (2 PDB entries)

5. Cellular retinol-binding protein III [63811] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [63812] (1 PDB entry)

6. Cellular retinol-binding protein IV [82157] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [82158] (1 PDB entry)

7. Der f 13 allergen [141467] (1 species)

   • Species House dust mite (Dermatophagoides farinae) [TaxId:6954] [141468] (1 PDB entry)
     Uniprot Q1M2P5 1-131

8. Epidermal fatty acid binding protein [50854] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50855] (6 PDB entries)

9. Fatty acid-binding protein [50858] (2 species)

   1. Species Desert locust (Schistocerca gregaria) [TaxId:7010] [50860] (1 PDB entry)

   2. Species Tobacco hornworm (Manduca sexta) [TaxId:7130] [50859] (1 PDB entry)

10. Fatty acid-binding protein homolog 1 [89366] (1 species)

    • Species Flat worm (Echinococcus granulosus) [TaxId:6210] [89367] (1 PDB entry)

11. Fatty acid-binding protein Sm14 [110276] (1 species)

    • Species Blood fluke (Schistosoma mansoni) [TaxId:6183] [110277] (2 PDB entries)
      Uniprot P29498

12. Ileal lipid-binding protein [50870] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [82159] (6 PDB entries)

    2. Species Pig (Sus scrofa) [TaxId:9823] [50871] (2 PDB entries)

13. Intestinal fatty acid binding protein [50851] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [50853] (6 PDB entries)

    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [50852] (12 PDB entries)
       Uniprot P02693

14. Liver basic fatty acid binding protein, LB_FABP [89368] (3 species)

    1. Species Argentine common toad (Bufo arenarum) [TaxId:38577] [89370] (1 PDB entry)

    2. Species Axolotl (Ambystoma mexicanum) [TaxId:8296] [141465] (1 PDB entry)
       Uniprot P81400 1-125

    3. Species Chicken (Gallus gallus) [TaxId:9031] [89369] (3 PDB entries)
       Uniprot P80226

15. Liver fatty acid binding protein [50866] (3 species)

    1. Species Chicken (Gallus gallus) [TaxId:9031] [256386] (3 PDB entries)

    2. Species Human (Homo sapiens) [TaxId:9606] [141464] (19 PDB entries)
       Uniprot P07148 1-127

    3. Species Norway rat (Rattus norvegicus) [TaxId:10116] [50867] (4 PDB entries)

16. Muscle fatty acid binding protein (m-fabp) [50848] (2 species)

    1. Species Cow (Bos taurus) [TaxId:9913] [50850] (1 PDB entry)

    2. Species Human (Homo sapiens) [TaxId:9606] [50849] (19 PDB entries)

17. P2 myelin protein [50868] (2 species)

    1. Species Cow (Bos taurus), caudal spinal root myelin [TaxId:9913] [50869] (1 PDB entry)

    2. Species Horse (Equus caballus) [TaxId:9796] [141466] (1 PDB entry)
       Uniprot P02690 1-131

18. automated matches [190295] (6 species)
    not a true protein

    1. Species Axolotl (Ambystoma mexicanum) [TaxId:8296] [187103] (1 PDB entry)

    2. Species Eel (Anguilla japonica) [TaxId:7937] [197394] (3 PDB entries)

    3. Species Human (Homo sapiens) [TaxId:9606] [187133] (57 PDB entries)

    4. Species Mouse (Mus musculus) [TaxId:10090] [226737] (4 PDB entries)

    5. Species Pygoscelis papua [TaxId:30457] [275573] (2 PDB entries)

    6. Species Zebrafish (Danio rerio) [TaxId:7955] [188008] (3 PDB entries)

More info for Family b.60.1.2: Fatty acid binding protein-like

Timeline for Family b.60.1.2: Fatty acid binding protein-like:

• Family b.60.1.2: Fatty acid binding protein-like first appeared (with stable ids) in SCOP 1.55
  
• Family b.60.1.2: Fatty acid binding protein-like appears in SCOPe 2.05
  
• Family b.60.1.2: Fatty acid binding protein-like appears in SCOPe 2.07
  
• Family b.60.1.2: Fatty acid binding protein-like appears in the current release, SCOPe 2.08