SCOP 1.75: Protein: TIMP-2

Lineage for Protein: TIMP-2

Root: SCOP 1.75
Class b: All beta proteins [48724] (174 folds)
Fold b.40: OB-fold [50198] (16 superfamilies)
barrel, closed or partly opened n=5, S=10 or S=8; greek-key
Superfamily b.40.3: TIMP-like [50242] (3 families)
Family b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP [50243] (2 proteins)
contains an irregular alpha+beta subdomain in the C-terminal extension
Protein TIMP-2 [50246] (2 species)

Species:

Cow (Bos taurus) [TaxId:9913] [50248] (3 PDB entries)
1. Domain for 1bqq:
  - Domain d1bqqt_: 1bqq T: [25237]
    Other proteins in same PDB: d1bqqm_
    complexed with k, zn
2. Domain for 1buv:
  - Domain d1buvt_: 1buv T: [25238]
    Other proteins in same PDB: d1buvm_
    complexed with ca, zn
3. Domain for 2e2d:
  - Domain d2e2dc1: 2e2d C:1001-1180 [131980]
    Other proteins in same PDB: d2e2da1
    automatically matched to d1bqqt_
    complexed with ca, zn

Human (Homo sapiens) [TaxId:9606] [50247] (3 PDB entries)

Domain for 1br9:
- Domain d1br9a_: 1br9 A: [25235]

Domains for 1gxd:

Domain d1gxdc_: 1gxd C: [70703]
Other proteins in same PDB: d1gxda1, d1gxda2, d1gxda3, d1gxda4, d1gxda5, d1gxda6, d1gxdb1, d1gxdb2, d1gxdb3, d1gxdb4, d1gxdb5, d1gxdb6
complexed with proMMP-2

Domain d1gxdd_: 1gxd D: [70704]
Other proteins in same PDB: d1gxda1, d1gxda2, d1gxda3, d1gxda4, d1gxda5, d1gxda6, d1gxdb1, d1gxdb2, d1gxdb3, d1gxdb4, d1gxdb5, d1gxdb6
complexed with proMMP-2
complexed with ca, so4, zn; mutant

Domain for 2tmp:
- Domain d2tmpa_: 2tmp A: [25236]
  mutant

More info for Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP

Timeline for Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP:

Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP first appeared (with stable ids) in SCOP 1.55
Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP appears in SCOP 1.73
Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP appears in SCOPe 2.01
Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP appears in the current release, SCOPe 2.08