Lineage for Protein: TIMP-2

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2049950Fold b.40: OB-fold [50198] (16 superfamilies)
    barrel, closed or partly opened n=5, S=10 or S=8; greek-key
  4. 2051080Superfamily b.40.3: TIMP-like [50242] (4 families) (S)
  5. 2051081Family b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP [50243] (2 protein domains)
    contains an irregular alpha+beta subdomain in the C-terminal extension
    automatically mapped to Pfam PF00965
  6. 2051094Protein TIMP-2 [50246] (2 species)

Species:

  1. 2051095Cow (Bos taurus) [TaxId:9913] [50248] (3 PDB entries)
    1. Domain for 1bqq:
    2. Domain for 1buv:
    3. Domain for 2e2d:
  2. 2051099Human (Homo sapiens) [TaxId:9606] [50247] (4 PDB entries)
    1. Domain for 1br9:
    2. Domains for 1gxd:
      1. 2051103Domain d1gxdc_: 1gxd C: [70703]
        Other proteins in same PDB: d1gxda1, d1gxda2, d1gxda3, d1gxda4, d1gxda5, d1gxda6, d1gxdb1, d1gxdb2, d1gxdb3, d1gxdb4, d1gxdb5, d1gxdb6
        complexed with proMMP-2
        complexed with ca, so4, zn
      2. 2051104Domain d1gxdd_: 1gxd D: [70704]
        Other proteins in same PDB: d1gxda1, d1gxda2, d1gxda3, d1gxda4, d1gxda5, d1gxda6, d1gxdb1, d1gxdb2, d1gxdb3, d1gxdb4, d1gxdb5, d1gxdb6
        complexed with proMMP-2
        complexed with ca, so4, zn
    3. Domain for 2tmp:
    4. Domains for 4ilw:
      1. 2051101Domain d4ilwa_: 4ilw A: [228945]
        Other proteins in same PDB: d4ilwd_, d4ilwf_
        automated match to d1br9a_
        complexed with ca, zn
      2. 2051102Domain d4ilwb_: 4ilw B: [228944]
        Other proteins in same PDB: d4ilwd_, d4ilwf_
        automated match to d1br9a_
        complexed with ca, zn

More info for Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP

Timeline for Protein TIMP-2 from b.40.3.1: Tissue inhibitor of metalloproteinases, TIMP: