Lineage for Family b.36.1.1: PDZ domain

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2785883Fold b.36: PDZ domain-like [50155] (1 superfamily)
    contains barrel, partly opened; n*=4, S*=8; meander; capped by alpha-helix
  4. 2785884Superfamily b.36.1: PDZ domain-like [50156] (7 families) (S)
    peptide-binding domain
  5. 2785885Family b.36.1.1: PDZ domain [50157] (47 proteins)
    Pfam PF00595

Proteins:

  1. 2785886Afadin [141269] (1 species)
  2. 2785890Alpha-actinin-2 associated LIM protein [110178] (1 species)
  3. 2785893Amyloid beta A4 precursor protein-binding family A member 1 (APBA1, X11) [141282] (1 species)
  4. 2785902Cask/Lin-2 [50160] (1 species)
  5. 2785906Channel associated protein of synapse-110 [141273] (1 species)
    Discs large homolog 2, PSD-93
  6. 2785909Discs large 5 protein KIAA0583 [101725] (1 species)
  7. 2785912Discs large protein homolog [50158] (1 species)
  8. 2785918DNA Regulating synaptic membrane exocytosis protein 2, RIMS2 [117176] (1 species)
  9. 2785921Enigma homolog ENH [117174] (1 species)
  10. 2785924Erbin [82085] (1 species)
  11. 2785931Glutamate receptor interacting protein [82083] (2 species)
    1. 2785932Species Mouse (Mus musculus) [TaxId:10090] [110177] (1 PDB entry)
      Uniprot Q925T6 461-570
    2. 2785934Species Norway rat (Rattus norvegicus) [TaxId:10116] [82084] (3 PDB entries)
  12. 2785939Glutamate receptor interacting protein 2, GRIP2 (KIAA1719) [110180] (1 species)
  13. 2785943Glutamate receptor-interacting protein 1, GRIP1 [101717] (1 species)
  14. 2785948GTPase-binding domain of the cell polarity protein par6 (Par-6B) [89315] (2 species)
    1. 2785949Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [101716] (3 PDB entries)
      Uniprot O97111 156-253; Cg5884-pa
    2. 2785953Species Mouse (Mus musculus) [TaxId:10090] [89316] (1 PDB entry)
  15. 2785956Harmonin [110182] (2 species)
    1. 2785957Species Human (Homo sapiens) [TaxId:9606] [141263] (1 PDB entry)
      Uniprot Q9Y6N9 201-301
    2. 2785959Species Mouse (Mus musculus) [TaxId:10090] [110183] (1 PDB entry)
      Uniprot Q9ES64 741-850
  16. 2785961hypothetical PDZ domain containing protein Uqcrc2 (4930408O21Rik) [117184] (1 species)
  17. 2785964Hypothetical protein KIAA0559 [101727] (1 species)
  18. 2785967Hypothetical protein KIAA1095 [101723] (1 species)
  19. 2785971Hypothetical protein KIAA1849 [101729] (1 species)
  20. 2785974Inad [63756] (1 species)
  21. 2785978KIAA1526 protein [101721] (1 species)
  22. 2785983Maguk p55 subfamily member 5 [141275] (1 species)
  23. 2785986Membrane associated guanylate kinase inverted-2 (MAGI-2, KIAA0705) [101719] (1 species)
  24. 2785993Multiple PDZ domain protein [141267] (1 species)
  25. 2786003Na+/H+ exchanger regulatory factor, NHERF [63754] (1 species)
  26. 2786009Neurabin-i [141277] (1 species)
  27. 2786012Neuronal nitric oxide synthase, NNOS [50166] (1 species)
  28. 2786017Partitioning-defective 3-like protein, PAR3-L (RIKEN cDNA 2810455b10) [117178] (1 species)
  29. 2786020PDZ domain containing protein 11, Pdzk11 [117182] (1 species)
  30. 2786023PDZ-LIM protein mystique [110186] (1 species)
  31. 2786026Phosphatase hPTP1e [50168] (2 species)
    1. 2786027Species Human (Homo sapiens) [TaxId:9606] [50169] (8 PDB entries)
    2. 2786044Species Mouse (Mus musculus) [TaxId:10090] [74930] (3 PDB entries)
  32. 2786048Presynaptic protein sap97 [141284] (1 species)
    PSD-95 homologue
  33. 2786051Regulating synaptic membrane exocytosis protein 1, RIMS1 [141279] (2 species)
    1. 2786052Species Human (Homo sapiens) [TaxId:9606] [141281] (1 PDB entry)
      Uniprot Q86UR5 585-694
    2. 2786054Species Norway rat (Rattus norvegicus) [TaxId:10116] [141280] (1 PDB entry)
      Uniprot Q9JIR4 597-705
  34. 2786056Regulator of G-protein signaling 3, RGS3 [117180] (2 species)
    1. 2786057Species Human (Homo sapiens) [TaxId:9606] [141264] (1 PDB entry)
      Uniprot P49796 300-376
    2. 2786060Species Mouse (Mus musculus) [TaxId:10090] [117181] (1 PDB entry)
      Uniprot Q9DC04 18-94
  35. 2786062Rhophilin-2 [110184] (1 species)
  36. 2786065Scribble (KIAA0147) [101731] (1 species)
  37. 2786081Segment polarity protein dishevelled homolog Dvl-2 [89313] (3 species)
    1. 2786082Species African clawed frog (Xenopus laevis) [TaxId:8355] [89314] (2 PDB entries)
    2. 2786090Species Human (Homo sapiens) [TaxId:9606] [188234] (5 PDB entries)
    3. 2786100Species Mouse (Mus musculus) [TaxId:10090] [101715] (1 PDB entry)
  38. 2786102Shank1, PDZ domain [101733] (2 species)
    SH3 and multiple ankyrin repeat domains protein 1
    1. 2786103Species Human (Homo sapiens) [TaxId:9606] [401374] (2 PDB entries)
    2. 2786108Species Norway rat (Rattus norvegicus) [TaxId:10116] [101734] (5 PDB entries)
  39. 2786124Synapse-associated protein 102 [101713] (1 species)
  40. 2786128Synaptic protein PSD-95 [50162] (2 species)
    Synonym: synapse associated protein 90, sap90
    duplication: contains three PDZ domains
    1. 2786129Species Human (Homo sapiens) [TaxId:9606] [74932] (10 PDB entries)
    2. 2786157Species Norway rat (Rattus norvegicus) [TaxId:10116] [50163] (14 PDB entries)
      Uniprot P31016 62-154
  41. 2786175Syntaxin binding protein 4 [141271] (1 species)
  42. 2786178Syntenin 1 [89311] (1 species)
  43. 2786213Syntrophin [50164] (1 species)
  44. 2786217Tight junction protein ZO-2, Tjp2 [141265] (1 species)
  45. 2786220Tyrosine-protein phosphatase non-receptor type 4, PTPN4 [141286] (1 species)
  46. 2786229Zasp (Cypher, Oracle 1) [101735] (2 species)
    1. 2786230Species Human (Homo sapiens) [TaxId:9606] [101736] (1 PDB entry)
    2. 2786232Species Mouse (Mus musculus) [TaxId:10090] [117173] (1 PDB entry)
      Uniprot Q9D130 1-83
  47. 2786234automated matches [190055] (6 species)
    not a true protein
    1. 2786235Species African clawed frog (Xenopus laevis) [TaxId:8355] [187076] (1 PDB entry)
    2. 2786238Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [255425] (2 PDB entries)
    3. 2786241Species Homo sapiens, influenza a virus [TaxId:9606] [193650] (1 PDB entry)
    4. 2786243Species Human (Homo sapiens) [TaxId:9606] [187785] (51 PDB entries)
    5. 2786344Species Mouse (Mus musculus) [TaxId:10090] [189198] (6 PDB entries)
    6. 2786359Species Norway rat (Rattus norvegicus) [TaxId:10116] [186775] (10 PDB entries)

More info for Family b.36.1.1: PDZ domain

Timeline for Family b.36.1.1: PDZ domain: