Lineage for Superfamily a.4.12: TrpR-like

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1981147Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 1984523Superfamily a.4.12: TrpR-like [48295] (4 families) (S)
    contains an extra shared helix after the HTH motif


  1. 1984524a.4.12.1: Trp repressor, TrpR [48296] (2 protein domains)
    intertwined dimer of identical 6-helical subunits
    automatically mapped to Pfam PF01371
  2. 1984567a.4.12.2: Chromosomal replication initiation factor DnaA C-terminal domain IV [81695] (1 protein)
    monomeric; contains additional N-terminal helices
  3. 1984577a.4.12.3: SPO1678-like [158345] (1 protein)
    Pfam PF06627; DUF1153
  4. 1984581a.4.12.0: automated matches [254246] (1 protein)
    not a true family

More info for Superfamily a.4.12: TrpR-like

Timeline for Superfamily a.4.12: TrpR-like: