SCOPe 2.08: Domain d7lmfa_: 7lmf A:

Lineage for d7lmfa_ (7lmf A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (8 species)
   contains an extra alpha-helical domain

7. Species Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049] [385979] (354 PDB entries)

8. Domain d7lmfa_: 7lmf A: [422033]
   automated match to d7n5za_
   complexed with y6g

Details for d7lmfa_

PDB Entry: 7lmf, 2.2 Å

PDB Description: sars-cov-2 3clpro in complex with 2-(benzotriazol-1-yl)-n-[4-(1h- imidazol-4-yl)phenyl]-n-(3-thienylmethyl)acetamide

PDB Compounds: (A:) 3C-like proteinase

SCOPe Domain Sequences for d7lmfa_:

Sequence; same for both SEQRES and ATOM records:

>d7lmfa_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {Severe acute respiratory syndrome coronavirus 2 [TaxId: 2697049]}
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllir
ksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegn
fygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc
sgvtf

Timeline for d7lmfa_:

• d7lmfa_ is new in SCOPe 2.08-stable