Lineage for Family b.47.1.4: Viral cysteine protease of trypsin fold

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2057856Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 protein domains)

Protein Domains:

  1. 20578572A cysteine proteinase [50607] (1 species)
  2. 20578613C cysteine protease (picornain 3C) [50604] (9 species)
    1. 2057862Species Foot-and-mouth disease virus [TaxId:12110] [159189] (2 PDB entries)
      Uniprot P49303 1657-1755! Uniprot P49303 1657-1857
    2. 2057865Species Human coxsackievirus a16 [TaxId:31704] [189721] (3 PDB entries)
    3. 2057869Species Human enterovirus 71 [TaxId:39054] [189720] (3 PDB entries)
    4. 2057884Species Human enterovirus b [TaxId:138949] [189732] (3 PDB entries)
    5. 2057891Species Human hepatitis a virus hu/northern africa/mbb/1978 [TaxId:12100] [186929] (2 PDB entries)
    6. 2057894Species Human hepatitis A virus [TaxId:208726] [50606] (5 PDB entries)
    7. 2057904Species Human poliovirus 1 Mahoney [TaxId:12081] [74978] (2 PDB entries)
    8. 2057909Species Human rhinovirus 2 [TaxId:12130] [50605] (3 PDB entries)
    9. 2057911Species Human rhinovirus sp. [TaxId:169066] [189940] (1 PDB entry)
  3. 2057913Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (6 species)
    contains an extra alpha-helical domain
    1. 2057914Species Human coronavirus 229E [TaxId:11137] [89348] (2 PDB entries)
    2. 2057919Species Human coronavirus [TaxId:443239] [188597] (3 PDB entries)
    3. 2057927Species Porcine transmissible gastroenteritis coronavirus [TaxId:11151] [193539] (1 PDB entry)
    4. 2057932Species Sars coronavirus sin2774 [TaxId:235410] [187498] (2 PDB entries)
    5. 2057935Species SARS coronavirus [TaxId:227859] [89349] (71 PDB entries)
    6. 2058030Species Transmissible gastroenteritis virus [TaxId:11149] [74980] (3 PDB entries)
  4. 2058045Norwalk-like virus processing protease [310746] (2 species)
    Pfam PF05416; 3C-like according to PubMed 16227288
    1. 2058046Species Chiba virus [TaxId:99565] [310999] (1 PDB entry)
    2. 2058051Species Norwalk virus [TaxId:11983] [311000] (2 PDB entries)
  5. 2058054automated matches [190384] (19 species)
    not a true protein
    1. 2058055Species Coxsackievirus b3 [TaxId:103903] [188647] (1 PDB entry)
    2. 2058057Species Enterovirus a71 [TaxId:39054] [279546] (12 PDB entries)
    3. 2058059Species Foot-and-mouth disease virus (strain a10-61) [TaxId:12112] [187901] (1 PDB entry)
    4. 2058061Species Foot-and-mouth disease virus [TaxId:12110] [187460] (1 PDB entry)
    5. 2058063Species Foot-and-mouth disease virus [TaxId:12112] [189099] (2 PDB entries)
    6. 2058070Species Human coxsackievirus B3 [TaxId:12072] [188738] (7 PDB entries)
    7. 2058080Species Human coxsackievirus [TaxId:12072] [188739] (11 PDB entries)
    8. 2058094Species Human enterovirus [TaxId:42789] [196804] (9 PDB entries)
    9. 2058104Species Human poliovirus 1 [TaxId:12081] [193776] (1 PDB entry)
    10. 2058106Species Human sars coronavirus [TaxId:227859] [187234] (2 PDB entries)
    11. 2058111Species Murine norovirus 1 [TaxId:223997] [311357] (5 PDB entries)
    12. 2058123Species Norovirus hu/1968/us [TaxId:524364] [311386] (1 PDB entry)
    13. 2058125Species Norwalk virus (strain gi/human/united states/norwalk/1968) [TaxId:524364] [311468] (3 PDB entries)
    14. 2058130Species Norwalk virus [TaxId:37129] [311216] (1 PDB entry)
    15. 2058133Species Rhinovirus c [TaxId:463676] [255484] (1 PDB entry)
    16. 2058135Species SARS coronavirus [TaxId:227859] [187411] (14 PDB entries)
    17. 2268274Species Porcine epidemic diarrhea virus [TaxId:28295] [311580] (2 PDB entries)
    18. 2270301Species Norwalk virus [TaxId:524364] [313606] (10 PDB entries)
    19. 2280302Species Echovirus 1 (strain human/egypt/farouk/1951) [TaxId:103908] [323603] (1 PDB entry)

More info for Family b.47.1.4: Viral cysteine protease of trypsin fold

Timeline for Family b.47.1.4: Viral cysteine protease of trypsin fold: