SCOPe 2.08: Domain d1de8a_: 1de8 A:

Lineage for d1de8a_ (1de8 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.151: DNase I-like [56218] (1 superfamily)
   contains beta-sandwich; duplication of alpha+beta motif

4. Superfamily d.151.1: DNase I-like [56219] (4 families)

5. Family d.151.1.1: DNase I-like [56220] (7 proteins)

6. Protein DNA repair endonuclease Hap1 [56223] (1 species)
   Major apurinic/apyrimidinic endonuclease APE1

7. Species Human (Homo sapiens) [TaxId:9606] [56224] (15 PDB entries)

8. Domain d1de8a_: 1de8 A: [41788]
   protein/DNA complex

Details for d1de8a_

PDB Entry: 1de8, 2.95 Å

PDB Description: human apurinic/apyrimidinic endonuclease-1 (ape1) bound to abasic dna

PDB Compounds: (A:) major apurinic/apyrimidinic endonuclease

SCOPe Domain Sequences for d1de8a_:

Sequence; same for both SEQRES and ATOM records:

>d1de8a_ d.151.1.1 (A:) DNA repair endonuclease Hap1 {Human (Homo sapiens) [TaxId: 9606]}
alyedppdhktspsgkpatlkicswnvdglrawikkkgldwvkeeapdilclqetkcsen
klpaelqelpglshqywsapsdkegysgvgllsrqcplkvsygigdeehdqegrvivaef
dsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvaheeidlrn
pkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsknvgwrl
dyfllshsllpalcdskirskalgsdhcpitlylal

Timeline for d1de8a_:

• d1de8a_ first appeared (with stable ids) in SCOP 1.55
  
• d1de8a_ appears in SCOPe 2.07