SCOPe 2.01: Domain d1dewa_: 1dew A:

Lineage for d1dewa_ (1dew A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.151: DNase I-like [56218] (1 superfamily)
   contains beta-sandwich; duplication of alpha+beta motif

4. Superfamily d.151.1: DNase I-like [56219] (4 families)

5. Family d.151.1.1: DNase I-like [56220] (7 proteins)

6. Protein DNA repair endonuclease Hap1 [56223] (1 species)
   Major apurinic/apyrimidinic endonuclease APE1

7. Species Human (Homo sapiens) [TaxId:9606] [56224] (7 PDB entries)

8. Domain d1dewa_: 1dew A: [41786]
   protein/DNA complex; complexed with so4

Details for d1dewa_

PDB Entry: 1dew, 2.65 Å

PDB Description: crystal structure of human ape1 bound to abasic dna

PDB Compounds: (A:) major apurinic/apyrimidinic endonuclease

SCOPe Domain Sequences for d1dewa_:

Sequence; same for both SEQRES and ATOM records:

>d1dewa_ d.151.1.1 (A:) DNA repair endonuclease Hap1 {Human (Homo sapiens) [TaxId: 9606]}
gpalyedppdhktspsgkpatlkicswnvdglrawikkkgldwvkeeapdilclqetkcs
enklpaelqelpglshqywsapsdkegysgvgllsrqcplkvsygigdeehdqegrviva
efdsfvlvtayvpnagrglvrleyrqrwdeafrkflkglasrkplvlcgdlnvaheeidl
rnpkgnkknagftpqerqgfgellqavpladsfrhlypntpyaytfwtymmnarsknvgw
rldyfllshsllpalcdskirskalgsdhcpitlylal

Timeline for d1dewa_:

• d1dewa_ first appeared (with stable ids) in SCOP 1.55
  
• d1dewa_ appears in SCOP 1.75
  
• d1dewa_ appears in SCOPe 2.02
  
• d1dewa_ appears in the current release, SCOPe 2.08