SCOPe 2.08: Domain d7msac_: 7msa C:

Lineage for d7msac_ (7msa C:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d7msac_: 7msa C: [405704]
   automated match to d3q95b_
   complexed with g9j, znm

Details for d7msac_

PDB Entry: 7msa, 2.24 Å

PDB Description: gdc-9545 in complex with estrogen receptor alpha

PDB Compounds: (C:) Estrogen receptor

SCOPe Domain Sequences for d7msac_:

Sequence, based on SEQRES records:

>d7msac_ a.123.1.1 (C:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltshdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydllleml

Sequence, based on observed residues (ATOM records):

>d7msac_ a.123.1.1 (C:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilysefseasmmglltnladrelvhminwakrvpgfvdlt
shdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllat
ssrfrmmnlqgeefvclksiillnsgvytftlksleekdhihrvldkitdtlihlmakag
ltlqqqhqrlaqlllilshirhmsnkgmehlysmkpsydllleml

Timeline for d7msac_:

• d7msac_ first appeared in SCOPe 2.07