SCOPe 2.08: Domain d6zorb1: 6zor B:307-547

Lineage for d6zorb1 (6zor B:307-547)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d6zorb1: 6zor B:307-547 [401577]
   Other proteins in same PDB: d6zora2, d6zorb2
   automated match to d3erta_
   complexed with qnh

Details for d6zorb1

PDB Entry: 6zor, 1.97 Å

PDB Description: oestrogen receptor ligand binding domain in complex with compound 28

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d6zorb1:

Sequence, based on SEQRES records:

>d6zorb1 a.123.1.1 (B:307-547) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemlda
h

Sequence, based on observed residues (ATOM records):

>d6zorb1 a.123.1.1 (B:307-547) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseypfseasmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytfleekdhihrvldkitdtlihlmakagltl
qqqhqrlaqlllilshirhmsnkgmehlysmvvpsydlllemldah

Timeline for d6zorb1:

• d6zorb1 first appeared in SCOPe 2.07