SCOPe 2.07: Domain d6xz8a_: 6xz8 A:

Lineage for d6xz8a_ (6xz8 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (95 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [196470] (50 PDB entries)

8. Domain d6xz8a_: 6xz8 A: [388352]
   Other proteins in same PDB: d6xz8b2
   automated match to d4dvqb_
   complexed with hec, o4t

Details for d6xz8a_

PDB Entry: 6xz8, 3 Å

PDB Description: structure of aldosterone synthase (cyp11b2) in complex with n-[(1r)-1- [5-(6-chloro-1,1-dimethyl-3-oxo-isoindolin-2-yl)-3- pyridyl]ethyl]methanesulfonamide

PDB Compounds: (A:) Cytochrome P450 11B2, mitochondrial

SCOPe Domain Sequences for d6xz8a_:

Sequence, based on SEQRES records:

>d6xz8a_ a.104.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tvlpfeampqhpgnrwlrllqiwreqgyehlhlemhqtfqelgpifrynlggprmvcvml
pedveklqqvdslhpcrmilepwvayrqhrghkcgvfllngpewrfnrlrlnpdvlspka
vqrflpmvdavardfsqalkkkvlqnargsltldvqpsifhytieasnlalfgerlglvg
hspssaslnflhalevmfkstvqlmfmprslsrwispkvwkehfeawdcifqygdnciqk
iyqelafnrpqhytgivaelllkaelsleaikansmeltagsvdttafpllmtlfelarn
pdvqqilrqeslaaaasisehpqkattelpllraalketlrlypvglflervvssdlvlq
nyhipagtlvqvflyslgrnaalfprperynpqrwldirgsgrnfhhvpfgfgmrqclgr
rlaeaemllllhhvlkhflvetltqedikmvysfilrpgtsplltfrain

Sequence, based on observed residues (ATOM records):

>d6xz8a_ a.104.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tvlpfeampqhpgnrwlrllqiwreqgyehlhlemhqtfqelgpifrynlggprmvcvml
pedveklqqvdslhpcrmilepwvayrqhrghkcgvfllngpewrfnrlrlnpdvlspka
vqrflpmvdavardfsqalkkkvlqnargsltldvqpsifhytieasnlalfgerlglvg
hspssaslnflhalevmfkstvqlmfmprslsrwispkvwkehfeawdcifqygdnciqk
iyqelafnrpqhytgivaelllkaelsleaikansmeltagsvdttafpllmtlfelarn
pdvqqilrqeslaaaasisehpqkattelpllraalketlrlypvglflervvssdlvlq
nyhipagtlvqvflyslgrnaalfprperynpqrwldinfhhvpfgfgmrqclgrrlaea
emllllhhvlkhflvetltqedikmvysfilrpgtsplltfrain

Timeline for d6xz8a_:

• d6xz8a_ is new in SCOPe 2.07-stable
  
• d6xz8a_ appears in the current release, SCOPe 2.08