SCOPe 2.08: Domain d6eiea1: 6eie A:562-1040

Lineage for d6eiea1 (6eie A:562-1040)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.117: Ras GEF [48365] (1 superfamily)
   multihelical

4. Superfamily a.117.1: Ras GEF [48366] (1 family)

5. Family a.117.1.1: Ras GEF [48367] (2 proteins)

6. Protein automated matches [269917] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [269918] (10 PDB entries)

8. Domain d6eiea1: 6eie A:562-1040 [364389]
   Other proteins in same PDB: d6eiea2
   automated match to d1nvus_
   mutant

Details for d6eiea1

PDB Entry: 6eie, 2.72 Å

PDB Description: ras guanine nucleotide exchange factor sos2 (rem-cdc25), with surface mutations

PDB Compounds: (A:) Son of sevenless homolog 2

SCOPe Domain Sequences for d6eiea1:

Sequence, based on SEQRES records:

>d6eiea1 a.117.1.1 (A:562-1040) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eqqlrlpspevyrfvvkdseenivfednlqsrsgipiikggtvvklierltyhmyadpnf
vrtflttyrsfckpqellsllierfeipepeptdadklaiekgeqpisadlkrfrkeyvq
pvqlrilnvfrhwvehhfydferdlyllerlesfissvrgkamkkwvesiakiirrkkqa
qangvshnitfesppppiewhiskpghietfdlmtlhpieiarqltllesdlyrkvqpse
lvgsvwtkedkeinspnllkmirhttnltlwfekciveaenfeervavlsriieilqvfq
dlnnfngvleivsavnsvsvyrldhtfealqerkrkildeavelsqdhfkkylvklksin
ppcvpffgiyltnilkteegnndfltrhgkdlinfskrrkvaeitgeiqqyqnqpyclri
epdmrrffenlnpmgsasekeftdylfnksleieprnpkqpprfprkstfslkspgirp

Sequence, based on observed residues (ATOM records):

>d6eiea1 a.117.1.1 (A:562-1040) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eqqlrlpspevyrfvvkdseenivfeipiikggtvvklierltyhmyadpnfvrtfltty
rsfckpqellsllierfeipepeptdadklaieqpisadlkrfrkeyvqpvqlrilnvfr
hwvehhfydferdlyllerlesfissvrgkamkkwvesiakiirrkkqaqsppppiewhi
skpghietfdlmtlhpieiarqltllesdlyrkvqpselvgsvwtkedkeinspnllkmi
rhttnltlwfekciveaenfeervavlsriieilqvfqdlnnfngvleivsavnsvsvyr
ldhtfealqerkrkildeavelsqdhfkkylvklksinppcvpffgiyltnilkteegnn
dfltrhlinfskrrkvaeitgeiqqyqnqpyclriepdmrrffenlnpmgsasekeftdy
lfnksleieprnpkqpprfprkstfslkspgirp

Timeline for d6eiea1:

• d6eiea1 first appeared in SCOPe 2.07