Lineage for d6guea1 (6gue A:1-298)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2980461Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2980462Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
    Uniprot P24941
  8. 2980805Domain d6guea1: 6gue A:1-298 [360978]
    Other proteins in same PDB: d6guea2, d6gueb1, d6gueb2, d6guec2, d6gued1, d6gued2
    automated match to d4fkla_
    complexed with fb8

Details for d6guea1

PDB Entry: 6gue (more details), 1.99 Å

PDB Description: cdk2/cyclina in complex with azd5438
PDB Compounds: (A:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d6guea1:

Sequence, based on SEQRES records: (download)

>d6guea1 d.144.1.7 (A:1-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtnnklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d6guea1 d.144.1.7 (A:1-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkitegvpstaireisllkelnhpnivk
lldvihtnnklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlh
rdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavd
iwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwar
qdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOPe Domain Coordinates for d6guea1:

Click to download the PDB-style file with coordinates for d6guea1.
(The format of our PDB-style files is described here.)

Timeline for d6guea1: