SCOPe 2.07: Domain d6fyzb_: 6fyz B:

Lineage for d6fyzb_ (6fyz B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (41 PDB entries)

8. Domain d6fyzb_: 6fyz B: [360770]
   Other proteins in same PDB: d6fyza2, d6fyzc2, d6fyzc3
   automated match to d4cbtb_
   complexed with ebe, na, zn

Details for d6fyzb_

PDB Entry: 6fyz, 2.15 Å

PDB Description: development and characterization of a cns-penetrant benzhydryl hydroxamic acid class iia histone deacetylase inhibitor

PDB Compounds: (B:) Histone deacetylase 4

SCOPe Domain Sequences for d6fyzb_:

Sequence, based on SEQRES records:

>d6fyzb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
prfttglvydtlmlkhqctcgsssshpehagriqsiwsrlqetglrgkcecirgrkatle
elqtvhseahtllygtnplnrqkldskkllgslasvfvrlpcggvgvdsdtiwnevhsag
aarlavgcvvelvfkvatgelkngfavvrppghhaeestpmgfcyfnsvavaakllqqrl
svskilivdwdvhhgngtqqafysdpsvlymslhryddgnffpgsgapdevgtgpgvgfn
vnmaftggldppmgdaeylaafrtvvmpiasefapdvvlvssgfdaveghptplggynls
arcfgyltkqlmglaggrivlalegghdltaicdaseacvsallgneldplpekvlqqrp
nanavrsmekvmeihskywrclq

Sequence, based on observed residues (ATOM records):

>d6fyzb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
prfttglvydtlmlkhqctcgsssshpehagriqsiwsrlqetglrgkcecirgrkatle
elqtvhseahtllygtnplnrrlpcggvgvdsdtiwnevhsagaarlavgcvvelvfkva
tgelkngfavvrppghhaeestpmgfcyfnsvavaakllqqrlsvskilivdwdvhhgng
tqqafysdpsvlymslhryddgnffpgsgapdevgtgpgvgfnvnmaftggldppmgdae
ylaafrtvvmpiasefapdvvlvssgfdaveghptplggynlsarcfgyltkqlmglagg
rivlalegghdltaicdaseacvsallgndplpekvlqqrpnanavrsmekvmeihskyw
rclq

Timeline for d6fyzb_:

• d6fyzb_ is new in SCOPe 2.07-stable
  
• d6fyzb_ appears in the current release, SCOPe 2.08