SCOPe 2.07: Family c.42.1.2: Histone deacetylase, HDAC

Lineage for Family c.42.1.2: Histone deacetylase, HDAC

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

Proteins:

1. HDAC homologue [52774] (1 species)

   • Species Aquifex aeolicus [TaxId:63363] [52775] (3 PDB entries)

2. Histone deacetylase 7, HDAC7 [159582] (1 species)
   HDAC7a

   • Species Human (Homo sapiens) [TaxId:9606] [159583] (9 PDB entries)
     Uniprot Q8WUI4 515-900

3. Histone deacetylase 8, HDAC8 [110587] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [110588] (5 PDB entries)
     Uniprot Q9BY41 13-375 ! Uniprot Q9BY41

4. automated matches [190786] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [188039] (41 PDB entries)

More info for Family c.42.1.2: Histone deacetylase, HDAC

Timeline for Family c.42.1.2: Histone deacetylase, HDAC:

• Family c.42.1.2: Histone deacetylase, HDAC first appeared (with stable ids) in SCOP 1.55
  
• Family c.42.1.2: Histone deacetylase, HDAC appears in SCOPe 2.06
  
• Family c.42.1.2: Histone deacetylase, HDAC appears in the current release, SCOPe 2.08