SCOPe 2.07: Domain d6c4aa1: 6c4a A:1-427

Lineage for d6c4aa1 (6c4a A:1-427)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families)

5. Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 proteins)
   forms a swapped dimer

6. Protein Isocitrate lyase [51642] (5 species)
   elaborated with additional subdomains

7. Species Mycobacterium tuberculosis [TaxId:652616] [322477] (5 PDB entries)

8. Domain d6c4aa1: 6c4a A:1-427 [353275]
   Other proteins in same PDB: d6c4aa2
   automated match to d5dqla_
   complexed with 3np, epe, mg, peg, pyr

Details for d6c4aa1

PDB Entry: 6c4a, 1.8 Å

PDB Description: crystal structure of 3-nitropropionate modified isocitrate lyase from mycobacterium tuberculosis with pyruvate

PDB Compounds: (A:) Isocitrate lyase 1

SCOPe Domain Sequences for d6c4aa1:

Sequence; same for both SEQRES and ATOM records:

>d6c4aa1 c.1.12.7 (A:1-427) Isocitrate lyase {Mycobacterium tuberculosis [TaxId: 652616]}
msvvgtpksaeqiqqewdtnprwkdvtrtysaedvvalqgsvveehtlarrgaevlweql
hdlewvnalgaltgnmavqqvraglkaiylsgwqvagdanlsghtypdqslypansvpqv
vrrinnalqradqiakiegdtsvenwlapivadgeagfggalnvyelqkaliaagvagsh
wedqlasekkxghlggkvliptqqhirtltsarlaadvadvptvviartdaeaatlitsd
vderdqpfitgertregfyrtkngiepciarakayapfadliwmetgtpdleaarqfsea
vkaeypdqmlayncspsfnwkkhlddatiakfqkelaamgfkfqfitlagfhalnysmfd
laygyaqnqmsayvelqerefaaeergytatkhqrevgagyfdriattvdpnssttaltg
steegqf

Timeline for d6c4aa1:

• d6c4aa1 is new in SCOPe 2.07-stable
  
• d6c4aa1 appears in the current release, SCOPe 2.08