SCOPe 2.08: Domain d1dr6a_: 1dr6 A:

Lineage for d1dr6a_ (1dr6 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)

6. Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)

7. Species Chicken (Gallus gallus) [TaxId:9031] [53606] (8 PDB entries)

8. Domain d1dr6a_: 1dr6 A: [34899]
   complexed with ca, hbi, mbo, nap

Details for d1dr6a_

PDB Entry: 1dr6, 2.4 Å

PDB Description: crystal structures of organomercurial-activated chicken liver dihydrofolate reductase complexes

PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d1dr6a_:

Sequence; same for both SEQRES and ATOM records:

>d1dr6a_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Chicken (Gallus gallus) [TaxId: 9031]}
vrslnsivavcqnmgigkdgnlpwpplrneykyfqrmtstshvegkqnavimgkktwfsi
peknrplkdrinivlsrelkeapkgahylskslddalalldspelkskvdmvwivggtav
ykaamekpinhrlfvtrilhefesdtffpeidykdfkllteypgvpadiqeedgiqykfe
vyqksv

Timeline for d1dr6a_:

• d1dr6a_ first appeared (with stable ids) in SCOP 1.55, called d1dr6__
  
• d1dr6a_ appears in SCOPe 2.07