SCOPe 2.07: Domain d2gjka1: 2gjk A:295-324,A:416-702

Lineage for d2gjka1 (2gjk A:295-324,A:416-702)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.19: Tandem AAA-ATPase domain [81268] (27 proteins)
   duplication: tandem repeat of two RecA-like (AAA) domains

6. Protein Upf1 [346071] (1 species)
   first domain includes small helical insert subdomain

7. Species Human (Homo sapiens) [TaxId:9606] [346290] (3 PDB entries)

8. Domain d2gjka1: 2gjk A:295-324,A:416-702 [344569]
   Other proteins in same PDB: d2gjka3, d2gjka4
   complexed with anp, mg

Details for d2gjka1

PDB Entry: 2gjk, 2.6 Å

PDB Description: Structural and functional insights into the human Upf1 helicase core

PDB Compounds: (A:) Regulator of nonsense transcripts 1

SCOPe Domain Sequences for d2gjka1:

Sequence, based on SEQRES records:

>d2gjka1 c.37.1.19 (A:295-324,A:416-702) Upf1 {Human (Homo sapiens) [TaxId: 9606]}
ryedayqyqnifgplvkleadydkklkesqXkstsfdrmqsalktfavdetsvsgyiyhk
llghevedviikcqlpkrftaqglpdlnhsqvyavktvlqrplsliqgppgtgktvtsat
ivyhlarqgngpvlvcapsniavdqltekihqtglkvvrlcaksreaidspvsflalhnq
irnmdsmpelqklqqlkdetgelssadekryralkrtaerellmnadvicctcvgagdpr
lakmqfrsilidestqatepecmvpvvlgakqlilvgdhcqlgpvvmckkaakaglsqsl
ferlvvlgirpirlqvqy

Sequence, based on observed residues (ATOM records):

>d2gjka1 c.37.1.19 (A:295-324,A:416-702) Upf1 {Human (Homo sapiens) [TaxId: 9606]}
ryedayqyqnifgplvkleadydkklkesqXkstsfdrmqsalktfavdetsvsgyiyhk
llghevedviikcqlpkrftaqglpdlnhsqvyavktvlqrplsliqgppgtgktvtsat
ivyhlarqgngpvlvcapsniavdqltekihqtglkvvrlcaksreaidspvsflalhnq
irnmdsmpelqklqqlkdessadekryralkrtaerellmnadvicctcvgagdprlakm
qfrsilidestqatepecmvpvvlgakqlilvgdhcqlgpvvmckkaakaglsqslferl
vvlgirpirlqvqy

Timeline for d2gjka1:

• d2gjka1 is new in SCOPe 2.07-stable
  
• d2gjka1 appears in the current release, SCOPe 2.08