SCOPe 2.08: Domain d5jcbf2: 5jcb F:77-378

Lineage for d5jcbf2 (5jcb F:77-378)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.1: Glutathione synthetase ATP-binding domain-like [56059] (11 families)

5. Family d.142.1.10: Tubulin tyrosine ligase (TTL) C-terminal domain-like [310626] (2 proteins)
   Pfam PF03133; PubMed 22020298

6. Protein Tubulin tyrosine ligase (TTL) C-terminal domain [310728] (3 species)

7. Species Chicken (Gallus gallus) [TaxId:9031] [311385] (176 PDB entries)

8. Domain d5jcbf2: 5jcb F:77-378 [344287]
   Other proteins in same PDB: d5jcba1, d5jcba2, d5jcbb1, d5jcbb2, d5jcbc1, d5jcbc2, d5jcbd1, d5jcbd2, d5jcbe_, d5jcbf1
   complexed with acp, ca, gdp, gol, gtp, imd, mes, mg, na, nv4, peg

Details for d5jcbf2

PDB Entry: 5jcb, 2.3 Å

PDB Description: microtubule depolymerizing agent podophyllotoxin derivative yjtsf1

PDB Compounds: (F:) Tubulin-tyrosine ligase

SCOPe Domain Sequences for d5jcbf2:

Sequence, based on SEQRES records:

>d5jcbf2 d.142.1.10 (F:77-378) Tubulin tyrosine ligase (TTL) C-terminal domain {Chicken (Gallus gallus) [TaxId: 9031]}
lvkliktspelsesctwfpesyviyptnlktpvapaqngirhlinntrtderevflaayn
rrregregnvwiakssagakgegilisseaselldfideqgqvhviqkylekplllepgh
rkfdirswvlvdhlyniylyregvlrtssepynsanfqdktchltnhciqkeysknygry
eegnemffeefnqylmdalnttlensillqikhiirsclmciepaistkhlhyqsfqlfg
fdfmvdeelkvwlievngapacaqklyaelcqgivdvaissvfpladtgqktsqptsifi
kl

Sequence, based on observed residues (ATOM records):

>d5jcbf2 d.142.1.10 (F:77-378) Tubulin tyrosine ligase (TTL) C-terminal domain {Chicken (Gallus gallus) [TaxId: 9031]}
lvkliktspelsctwfpesyiypderevflaayngnvwiaksisseaselldfihviqky
lekplllepghrkfdirswvlvdhlyniylyregvlrtssepynsaktchltnhciqkey
ygryeegnemffeefnqylmdalnttlensillqikhiirsclmciepaistkhlhyqsf
qlfgfdfmvdeelkvwlievngapacaqklyaelcqgivdvaissvfplasifikl

Timeline for d5jcbf2:

• d5jcbf2 first appeared in SCOPe 2.07