SCOPe 2.08: Domain d5nvxe1: 5nvx E:17-112

Lineage for d5nvxe1 (5nvx E:17-112)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.42: POZ domain [54694] (1 superfamily)
   core: beta(2)-alpha(2)-beta(2)-alpha(2); 2 layers a/b; mixed sheet: 2143

4. Superfamily d.42.1: POZ domain [54695] (3 families)

5. Family d.42.1.1: BTB/POZ domain [54696] (6 proteins)

6. Protein Elongin C [54699] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54700] (56 PDB entries)

8. Domain d5nvxe1: 5nvx E:17-112 [339167]
   Other proteins in same PDB: d5nvxa_, d5nvxb2, d5nvxc_, d5nvxd_, d5nvxe2, d5nvxf_, d5nvxg_, d5nvxh2, d5nvxi_, d5nvxj_, d5nvxk2, d5nvxl_
   automated match to d1lm8c_
   complexed with 4yy

Details for d5nvxe1

PDB Entry: 5nvx, 2.2 Å

PDB Description: pvhl:elob:eloc in complex with (2s,4r)-1-((s)-2-(1- fluorocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-n-(4- (4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 10)

PDB Compounds: (E:) Elongin-C

SCOPe Domain Sequences for d5nvxe1:

Sequence, based on SEQRES records:

>d5nvxe1 d.42.1.1 (E:17-112) Elongin C {Human (Homo sapiens) [TaxId: 9606]}
myvklissdghefivkrehaltsgtikamlsgpgqfaenetnevnfreipshvlskvcmy
ftykvrytnssteipefpiapeialellmaanfldc

Sequence, based on observed residues (ATOM records):

>d5nvxe1 d.42.1.1 (E:17-112) Elongin C {Human (Homo sapiens) [TaxId: 9606]}
myvklissdghefivkrehaltsgtikamlsgnetnevnfreipshvlskvcmyftykvr
ytnssteipefpiapeialellmaanfldc

Timeline for d5nvxe1:

• d5nvxe1 first appeared in SCOPe 2.06
  
• d5nvxe1 appears in SCOPe 2.07