SCOPe 2.08: Domain d5mmsc_: 5mms C:

Lineage for d5mmsc_ (5mms C:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.79: Tryptophan synthase beta subunit-like PLP-dependent enzymes [53685] (1 superfamily)
   consists of two similar domains related by pseudo dyad; duplication
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 3214

4. Superfamily c.79.1: Tryptophan synthase beta subunit-like PLP-dependent enzymes [53686] (2 families)

5. Family c.79.1.1: Tryptophan synthase beta subunit-like PLP-dependent enzymes [53687] (9 proteins)

6. Protein Cystathionine beta-synthase [64174] (1 species)
   PLP-dependent hemoprotein

7. Species Human (Homo sapiens) [TaxId:9606] [64175] (3 PDB entries)

8. Domain d5mmsc_: 5mms C: [333795]
   automated match to d1m54a_
   complexed with hem, na, plp

Details for d5mmsc_

PDB Entry: 5mms, 2.8 Å

PDB Description: human cystathionine beta-synthase (cbs) p.p49l delta409-551 variant

PDB Compounds: (C:) cystathionine beta-synthase

SCOPe Domain Sequences for d5mmsc_:

Sequence, based on SEQRES records:

>d5mmsc_ c.79.1.1 (C:) Cystathionine beta-synthase {Human (Homo sapiens) [TaxId: 9606]}
irpdalsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqy
rnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpe
gsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqeg
llcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqk

Sequence, based on observed residues (ATOM records):

>d5mmsc_ c.79.1.1 (C:) Cystathionine beta-synthase {Human (Homo sapiens) [TaxId: 9606]}
irpdalsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpssekvdvlralgaeivrtpdspeshvgvawrlkneipnshildqyrnasnpla
hydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaepe
elnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsag
stvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqk

Timeline for d5mmsc_:

• d5mmsc_ first appeared in SCOPe 2.06
  
• d5mmsc_ appears in SCOPe 2.07