SCOP 1.63: Domain d1reqd2: 1req D:476-638

Lineage for d1reqd2 (1req D:476-638)

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.23: Flavodoxin-like [52171] (16 superfamilies)
   3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345

4. Superfamily c.23.6: Cobalamin (vitamin B12)-binding domain [52242] (1 family)

5. Family c.23.6.1: Cobalamin (vitamin B12)-binding domain [52243] (3 proteins)

6. Protein Methylmalonyl-CoA mutase C-terminal domains of alpha and beta subunits [52249] (1 species)
   Both subunits are clearly related but only one (alpha) is active and binds B12

7. Species Propionibacterium freudenreichii, subsp. shermanii [TaxId:1744] [52250] (8 PDB entries)

8. Domain d1reqd2: 1req D:476-638 [31250]
   Other proteins in same PDB: d1reqa1, d1reqb1, d1reqc1, d1reqd1
   complexed with b12, dca, gol; mutant

Details for d1reqd2

PDB Entry: 1req, 2 Å

PDB Description: methylmalonyl-coa mutase

SCOP Domain Sequences for d1reqd2:

Sequence; same for both SEQRES and ATOM records:

>d1reqd2 c.23.6.1 (D:476-638) Methylmalonyl-CoA mutase C-terminal domains of alpha and beta subunits {Propionibacterium freudenreichii, subsp. shermanii}
tkpfpaaparkglawhrdsevfeqlmdrstsvserpkvflaclgtrrdfggregfsspvw
hiagidtpqveggttaeiveafkksgaqvadlcssakvyaqqglevakalkaagakalyl
sgafkefgddaaeaeklidgrlfmgmdvvdtlsstldilgvak

Timeline for d1reqd2:

• d1reqd2 first appeared (with stable ids) in SCOP 1.55
  
• d1reqd2 appears in SCOP 1.61
  
• d1reqd2 appears in SCOP 1.65
  
• d1reqd2 appears in the current release, SCOPe 2.08