SCOPe 2.08: Domain d3uq1a3: 3uq1 A:386-575

Lineage for d3uq1a3 (3uq1 A:386-575)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (5 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein DNA polymerase lambda [102943] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102944] (27 PDB entries)

8. Domain d3uq1a3: 3uq1 A:386-575 [306666]
   Other proteins in same PDB: d3uq1a1, d3uq1a2
   automated match to d2bcqa3
   protein/DNA complex; complexed with cl, f2a, mg, mn, na

Details for d3uq1a3

PDB Entry: 3uq1, 2.01 Å

PDB Description: Crystal structure of the pre-catalytic ternary complex of polymerase lambda with a dATP analog opposite a templating T and a rCMP at the primer terminus.

PDB Compounds: (A:) DNA polymerase lambda

SCOPe Domain Sequences for d3uq1a3:

Sequence, based on SEQRES records:

>d3uq1a3 d.218.1.2 (A:386-575) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdgrshrgifs
rlldslrqegfltddlvkgetkylgvcrlpgpgrrhrrldiivvpysefacallyftgsa
hfnrsmralaktkgmslsehalstavvrnthgakvgpgrvlptptekdvfrllglpyrep
aerdw

Sequence, based on observed residues (ATOM records):

>d3uq1a3 d.218.1.2 (A:386-575) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdggifsrlld
slrqegfltddlvkgetkylgvcrlpgpgrrhrrldiivvpysefacallyftgsahfnr
smralaktkgmslsehalstavvrnthgakvgpgrvlptptekdvfrllglpyrepaerd
w

Timeline for d3uq1a3:

• d3uq1a3 first appeared in SCOPe 2.06
  
• d3uq1a3 appears in SCOPe 2.07