SCOPe 2.07: Domain d3u85a2: 3u85 A:231-581

Lineage for d3u85a2 (3u85 A:231-581)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.8: TPR-like [48452] (10 families)

5. Family a.118.8.1: Tetratricopeptide repeat (TPR) [48453] (21 proteins)
   this is a repeat family; one repeat unit is 1zb1 A:166-231 found in domain

6. Protein Menin C-terminal domain [310725] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [310974] (33 PDB entries)

8. Domain d3u85a2: 3u85 A:231-581 [306643]
   Other proteins in same PDB: d3u85a1, d3u85b1, d3u85b2

Details for d3u85a2

PDB Entry: 3u85, 3 Å

PDB Description: crystal structure of human menin in complex with mll1

PDB Compounds: (A:) Menin

SCOPe Domain Sequences for d3u85a2:

Sequence, based on SEQRES records:

>d3u85a2 a.118.8.1 (A:231-581) Menin C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
drkmevafmvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleele
ptpgrpdpltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqd
ynycredeeiykeffevandvipnllkeaaslleageerpgeqsqgtqsqgsalqdpecf
ahllrfydgickweegsptpvlhvgwatflvqslgrfegqvrqkvrivsgtvagtargpe
ggstaqvpaptaspppegpvltfqsekmkgmkellvatkinssaiklqlta

Sequence, based on observed residues (ATOM records):

>d3u85a2 a.118.8.1 (A:231-581) Menin C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
drkmevafmvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleele
ptpgrpdpltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqd
ynycredeeiykeffevandvipnllkeaaslleasalqdpecfahllrfydgickweeg
sptpvlhvgwatflvqslgrfegqvrqkvrivsgtvagtargpvltfqsekmkgmkellv
atkinssaiklqlta

Timeline for d3u85a2:

• d3u85a2 first appeared in SCOPe 2.06
  
• d3u85a2 appears in the current release, SCOPe 2.08